Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 6/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29509761 | 1.00 | SYK (0.44) | SYKATRRORCMAPKAPK2P2RX3 | |
| SCHEMBL1010435 | 0.85 | ATR (0.46) | ATRRORCMAPKAPK2NAMPTMAP4K4 | |
| SCHEMBL12902766 | 0.84 | ATR (0.45) | ATRRORCMAPKAPK2NAMPTMAP4K4 | |
| SCHEMBL29813612 | 0.84 | SYK (0.45) | SYKRORCMAPKAPK2NAMPTMAP4K4 | |
| SCHEMBL15081332 | 0.84 | SYK (0.45) | SYKRORCMAPKAPK2NAMPTMAP4K4 | |
| SCHEMBL30954955 | 0.83 | RORC (0.41) | SYKATRRORCMAPKAPK2NAMPT | |
| SCHEMBL909598 | 0.83 | AR (0.48) | ATRRORCMAPKAPK2NAMPTAR | |
| SCHEMBL14018435 | 0.83 | ATR (0.44) | SYKATRRORCMAPKAPK2NAMPT | |
| SCHEMBL30004261 | 0.83 | SYK (0.44) | SYKRORCMAPKAPK2NAMPTMAP4K4 | |
| SCHEMBL29178680 | 0.83 | SYK (0.44) | SYKRORCMAPKAPK2NAMPTMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122055370-A | And cyclic nitrogen-containing compound, crystal form thereof, preparation method and application thereof | 杭州圣域生物医药科技有限公司 | 2026-05-15 | — | — | CN | disclosed |
| US-20260022118-A1 | HETEROCYCLIC COMPOUNDS AS NRAS INHIBITORS | UNIV TEXAS (US) | 2026-01-22 | — | — | US | disclosed |
| EP-4441041-B1 | HERBICIDAL PYRAZOLE PYRIMIDINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-09-17 | — | — | EP | disclosed |
| EP-4585599-A1 | NITROGEN-CONTAINING FUSED RING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | Hangzhou Synrx Therapeutics Biomedical Technology Co., Ltd. (CN) | 2025-07-16 | — | — | EP | disclosed |
| WO-2025051157-A1 | PYRIDINE-2(1H)-KETONE PRMT5-MTA INHIBITOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2025-03-13 | — | — | WO | disclosed |
| US-20250042876-A1 | HERBICIDAL PYRAZOLE PYRIMIDINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-02-06 | — | — | US | disclosed |
| US-12139499-B2 | Heteroaryl compounds for treating Huntington's disease | PTC THERAPEUTICS, INC. (US) | 2024-11-12 | — | — | US | disclosed |
| WO-2024215862-A2 | HETEROCYCLIC COMPOUNDS AS NRAS INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-10-17 | — | — | WO | disclosed |
| EP-4441041-A1 | HERBICIDAL PYRAZOLE PYRIMIDINE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2024-10-09 | — | — | EP | disclosed |
| EP-3814345-B1 | HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS INC (US) | 2024-09-25 | — | — | EP | disclosed |
| US-9440976-B2 | 1,7-diazacarbazoles and methods of use | GENENTECH, INC. (US) | 2016-09-13 | — | — | US | disclosed |
| US-20150328195-A1 | 1,7-DIAZACARBAZOLES AND METHODS OF USE | GENENTECH, INC. (US) | 2015-11-19 | — | — | US | disclosed |
| US-20150328195-A1 | 1,7-DIAZACARBAZOLES AND METHODS OF USE | GENENTECH, INC. (US) | 2015-11-19 | — | — | US | disclosed |
| US-20140171407-A1 | 1,7-DIAZACARBAZOLES AND METHODS OF USE | GENENTECH, INC. (US) | 2014-06-19 | — | — | US | disclosed |
| US-20140171407-A1 | 1,7-DIAZACARBAZOLES AND METHODS OF USE | GENENTECH, INC. (US) | 2014-06-19 | — | — | US | disclosed |
| EP-2513110-A1 | 1, 7 - DIAZACARBAZOLES AND THEIR USE IN THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2012-10-24 | — | — | EP | disclosed |
| US-20110183938-A1 | 1,7-DIAZACARBAZOLES AND METHODS OF USE | GENENTECH, INC. (US) | 2011-07-28 | — | — | US | disclosed |
| US-20110183938-A1 | 1,7-DIAZACARBAZOLES AND METHODS OF USE | GENENTECH, INC. (US) | 2011-07-28 | — | — | US | disclosed |
| WO-2011073263-A1 | 1, 7 - DIAZACARBAZOLES AND THEIR USE IN THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011073263-A1 | 1, 7 - DIAZACARBAZOLES AND THEIR USE IN THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150328195-A1 | 1,7-DIAZACARBAZOLES AND METHODS OF USE | CHEK1, CHEK2, BUB1B | SYK 2577/4885ATR 40/4885RORC 2095/4885 |
| US-12139499-B2 | Heteroaryl compounds for treating Huntington's disease | HTT, HYPK, HDAC6 | SYK 3657/4885ATR 3697/4885RORC 2196/4885 |
| US-20110183938-A1 | 1,7-DIAZACARBAZOLES AND METHODS OF USE | CHEK1, CHEK2, BUB1B | SYK 2577/4885ATR 40/4885RORC 2095/4885 |
| US-20260022118-A1 | HETEROCYCLIC COMPOUNDS AS NRAS INHIBITORS | NRAS, KRAS, HRAS | SYK 786/4885ATR 148/4885RORC 650/4885 |
| US-20140171407-A1 | 1,7-DIAZACARBAZOLES AND METHODS OF USE | CHEK1, CHEK2, BUB1B | SYK 2577/4885ATR 40/4885RORC 2095/4885 |
| US-20250042876-A1 | HERBICIDAL PYRAZOLE PYRIMIDINE COMPOUNDS | DPYD, DHFR, DHX35 | SYK 3030/4885ATR 1252/4885RORC 2657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.