Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 8/20 | 0.31 |
| ▸ | CA2 | P00918 | 8/20 | 0.31 |
| ▸ | CA9 | Q16790 | 7/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA7 | P43166 | 3/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17633944 | 0.98 | MEN1 (0.31) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL17633872 | 0.98 | — | — | |
| SCHEMBL17633845 | 0.96 | — | — | |
| SCHEMBL17633937 | 0.92 | ALDH1A1 (0.31) | — | |
| SCHEMBL17633936 | 0.92 | ALDH1A1 (0.31) | — | |
| SCHEMBL19283052 | 0.90 | ALDH1A1 (0.30) | — | |
| SCHEMBL19283053 | 0.90 | ALDH1A1 (0.30) | — | |
| SCHEMBL17633833 | 0.86 | THRB (0.35) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL17633866 | 0.84 | CA1 (0.31) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL17633900 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11028256-B2 | Silica-containing rubber compositions containing specified coupling agents and related methods | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2021-06-08 | — | — | US | disclosed |
| US-20200123349-A1 | SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2020-04-23 | — | — | US | disclosed |
| US-20170247532-A1 | SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC | 2017-08-31 | — | — | US | disclosed |
| EP-3197950-A1 | SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS | Bridgestone Americas Tire Operations, LLC (US) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016048935-A1 | SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2016-03-31 | — | — | WO | disclosed |