SCHEMBL176354

SCHEMBL176354

C=C(C)C(O)=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4625286 1.00 TDP1 (0.35)
SCHEMBL5347394 1.00 TDP1 (0.35)
Hydrochloric Acid SCHEMBL11753357 0.96
Benzene SCHEMBL17022337 0.92 TAS2R38 (0.33)
SCHEMBL11753346 0.78
SCHEMBL6840418 0.76
SCHEMBL8584045 0.76
SCHEMBL21437104 0.76
SCHEMBL9246660 0.73
SCHEMBL2384524 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 786 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12269205-B2 Eyewear lens creation using additive techniques with diffuse light INDIZEN OPTICAL TECHNOLOGIES S.L. (ES) 2025-04-08 US claimed
US-12173176-B2 Liquid polymerizable composition comprising mineral nanoparticles and its use to manufacture an optical article NIKON CORPORATION (JP) 2024-12-24 US claimed
EP-4229100-A1 EYEWEAR LENS CREATION USING ADDITIVE TECHNIQUES WITH DIFFUSE LIGHT Indizen Optical Technologies S.L. (US) 2023-08-23 EP claimed
US-11725136-B2 Process for manufacturing light absorbing polymer matrix ESSILOR INTERNATIONAL (FR) 2023-08-15 US claimed
US-20230219287-A1 EYEWEAR LENS CREATION USING ADDITIVE TECHNIQUES WITH DIFFUSE LIGHT INDIZEN OPTICAL TECHNOLOGIES, S.L. (ES) 2023-07-13 US claimed
US-11642319-B2 Targeted nanogels for urinary bladder therapies THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2023-05-09 US claimed
US-11635547-B2 Composition for the manufacture of an ophthalmic lens comprising an encapsulated light-absorbing additive ESSILOR INTERNATIONAL (FR) 2023-04-25 US claimed
US-11633907-B2 Eyewear lens creation using additive techniques with diffuse light INDIZEN OPTICAL TECHNOLOGIES S.L. (ES) 2023-04-25 US claimed
EP-3497488-B2 OPHTALMIC LENS COMPRISING AN ENCAPSULATED LIGHT-ABSORBING ADDITIVE ESSILOR INT (FR) 2023-03-22 EP claimed
US-20220187628-A1 OPTICAL DEVICE WITH TRANSMISSION INHIBITION PLATEAU IN BLUE SPECTRAL RANGE HUE AI LLC (US) 2022-06-16 US claimed
EP-0997134-A1 Use of a specific particulate phase in a cosmetic composition L'OREAL (FR) 2000-05-03 EP claimed
WO-1999038924-A1 COATING COMPOSITION SOLA INTERNATIONAL HOLDINGS LTD. (AU) 1999-08-05 WO claimed
WO-1998024761-A1 ACRYLIC THIO MONOMERS SOLA INTERNATIONAL HOLDINGS LTD. (AU) 1998-06-11 WO claimed
US-5741831-A Polymerizable compositions based on thio (meth) acrylate monomers, polymers with a low yellow index obtained from such compositions, and corresponding ophthalmic lenses ESSILOR INTERNATIONAL - COMPAGNIE GENERALE D'OPTIQUE (FR) 1998-04-21 US claimed
EP-0745620-B1 Polymerisable compositions based on thio(meth)acrylate monomers, polymers having low yellowness index made from these compositions and ophthalmic lenses made therefrom ESSILOR INT (FR) 1997-10-29 EP claimed
EP-0745620-A1 Polymerisable compositions based on thio(meth)acrylate monomers, polymers having low yellowness index made from these compositions and ophthalmic lenses made therefrom ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1996-12-04 EP claimed
US-5488128-A Monomer for high refractive index plastics ROEHM GMBH CHEMISCHE FABRIK (DE) 1996-01-30 US claimed
WO-1995024386-A1 S-(φ-HYDROXYALKYL) ESTERS OF THIOACRYLIC AND THIOMETHACRYLIC ACIDS, THEIR PREPARATION AND POLYMERS MADE THEREFROM CURATORS OF THE UNIVERSITY OF MISSOURI (US) 1995-09-14 WO claimed
US-4931521-A Optical materials composed of resin from thioacrylat esters NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1990-06-05 US claimed
EP-0273710-A2 Resin having high refractive index, process for producing said resin and optical materials composed of said resin Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1988-07-06 EP claimed