Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176354 | 1.00 | — | — | |
| SCHEMBL4625286 | 1.00 | TDP1 (0.35) | TDP1ALDH1A1TP53TSHR | |
| Hydrochloric Acid SCHEMBL11753357 | 0.96 | — | — | |
| Benzene SCHEMBL17022337 | 0.92 | TAS2R38 (0.33) | TDP1ALDH1A1 | |
| SCHEMBL11753346 | 0.78 | — | — | |
| SCHEMBL6840418 | 0.76 | — | — | |
| SCHEMBL8584045 | 0.76 | — | — | |
| SCHEMBL21437104 | 0.76 | — | — | |
| SCHEMBL9246660 | 0.73 | — | — | |
| SCHEMBL2384524 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172140-B1 | CROSSLINKING POLYMERIC CASTING COMPOSITION INCLUDING AN (METH)ACRYLIC TRI- OR TETRA-THIOL SUCH AS 4-MERCAPTOMETHYL-3,6-DITHIA-1,8-OCTANEDITHIOL TRITHIOMETHACRYLATE; OPHTHALMIC LENSE | SOLA INTERNATIONAL HOLDINGS LTD (AU) | 2001-01-09 | — | — | US | claimed |
| WO-1998024761-A1 | ACRYLIC THIO MONOMERS | SOLA INTERNATIONAL HOLDINGS LTD. (AU) | 1998-06-11 | — | — | WO | claimed |
| EP-1952184-B1 | PHOTOCHROMIC MULTIFOCAL OPTICAL ARTICLE | TRANSITIONS OPTICAL INC (US) | 2021-08-11 | — | — | EP | disclosed |
| US-7258437-B2 | Photochromic multifocal optical article | TRANSITIONS OPTICAL, INC. (US) | 2007-08-21 | — | — | US | disclosed |
| US-20070052922-A1 | Photochromic multifocal optical article | TRANSITIONS OPTICAL LIMITED (IE) | 2007-03-08 | — | — | US | disclosed |
| US-6172140-B1 | CROSSLINKING POLYMERIC CASTING COMPOSITION INCLUDING AN (METH)ACRYLIC TRI- OR TETRA-THIOL SUCH AS 4-MERCAPTOMETHYL-3,6-DITHIA-1,8-OCTANEDITHIOL TRITHIOMETHACRYLATE; OPHTHALMIC LENSE | SOLA INTERNATIONAL HOLDINGS LTD (AU) | 2001-01-09 | — | — | US | disclosed |
| WO-1998024761-A1 | ACRYLIC THIO MONOMERS | SOLA INTERNATIONAL HOLDINGS LTD. (AU) | 1998-06-11 | — | — | WO | disclosed |