Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDA | P32320 | 8/20 | 0.33 |
| ▸ | TK1 | P04183 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17635427 | 0.83 | TK1 (0.33) | CDATK1LMNASMN1; SMN2ALB | |
| SCHEMBL12865276 | 0.83 | TK1 (0.33) | CDATK1LMNASMN1; SMN2ALB | |
| SCHEMBL12865604 | 0.72 | — | — | |
| SCHEMBL21560996 | 0.70 | TK1 (0.44) | TK1LMNASMN1; SMN2 | |
| SCHEMBL19129852 | 0.67 | RNASE1 (0.36) | CDATK1ALBPKM | |
| Alovudine SCHEMBL12296837 | 0.65 | TK1 (0.68) | TK1LMNAALBPKM | |
| Alovudine SCHEMBL20769856 | 0.65 | TK1 (0.68) | TK1LMNAALBPKM | |
| Alovudine SCHEMBL9849822 | 0.65 | TK1 (0.68) | TK1LMNAALBPKM | |
| Alovudine SCHEMBL10380714 | 0.65 | TK1 (0.68) | TK1LMNAALBPKM | |
| Alovudine SCHEMBL13020428 | 0.65 | TK1 (0.68) | TK1LMNAALBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296776-B2 | Substituted nucleoside derivatives with antiviral and antimicrobial properties | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2016-03-29 | — | — | US | disclosed |