⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1494100 | 1.00 | — | — | |
| SCHEMBL17914132 | 1.00 | — | — | |
| SCHEMBL14417625 | 1.00 | — | — | |
| SCHEMBL20390944 | 0.80 | LMNA (0.58) | — | |
| SCHEMBL28348602 | 0.78 | TDP1 (0.60) | — | |
| E968 SCHEMBL28433972 | 0.76 | LMNA (0.50) | — | |
| SCHEMBL11145479 | 0.75 | LMNA (0.42) | — | |
| SCHEMBL14554334 | 0.75 | LMNA (0.42) | — | |
| SCHEMBL1780664 | 0.75 | LMNA (0.42) | — | |
| SCHEMBL12761287 | 0.75 | TDP1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448600-B1 | COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | INSERM INST NAT DE LA SANTÉ ET DE LA RECH MÉDICALE (FR) | 2016-03-30 | — | — | EP | disclosed |