Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 10/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7925240 | 1.00 | UGCG (0.61) | UGCGOPRK1ATMMITFALDH1A1 | |
| SCHEMBL7102820 | 0.90 | OPRK1 (0.60) | UGCGOPRK1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL299718 | 0.90 | OPRK1 (0.60) | UGCGOPRK1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7099886 | 0.90 | OPRK1 (0.60) | UGCGOPRK1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17122952 | 0.89 | UGCG (0.55) | UGCGOPRK1ITGB3ITGA2BCYP3A4 | |
| SCHEMBL7102877 | 0.89 | OPRK1 (0.59) | UGCGOPRK1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7925792 | 0.89 | OPRK1 (0.54) | UGCGOPRK1HIF1AITGB3ITGA2B | |
| SCHEMBL16695234 | 0.88 | UGCG (0.62) | UGCGOPRK1ITGB3ITGA2B | |
| SCHEMBL7923099 | 0.88 | TP53 (0.53) | UGCGOPRK1ITGB3ITGA2B | |
| SCHEMBL12407050 | 0.88 | TP53 (0.53) | UGCGOPRK1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349255-B1 | 2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORP (US) | 2016-03-30 | — | — | EP | disclosed |