Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.52 |
| ▸ | UGCG | Q16739 | 8/20 | 0.49 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12407050 | 1.00 | TP53 (0.53) | TP53OPRK1UGCGCCR1ITGB3 | |
| SCHEMBL7102820 | 0.92 | OPRK1 (0.60) | TP53OPRK1UGCGITGB3ITGA2B | |
| SCHEMBL299718 | 0.92 | OPRK1 (0.60) | TP53OPRK1UGCGITGB3ITGA2B | |
| SCHEMBL7099886 | 0.92 | OPRK1 (0.60) | TP53OPRK1UGCGITGB3ITGA2B | |
| SCHEMBL17122952 | 0.91 | UGCG (0.55) | OPRK1UGCGITGB3ITGA2B | |
| SCHEMBL7102877 | 0.91 | OPRK1 (0.59) | TP53OPRK1UGCGITGB3ITGA2B | |
| SCHEMBL29880827 | 0.89 | OPRK1 (0.52) | OPRK1UGCGCCR1ITGB3ITGA2B | |
| SCHEMBL7925792 | 0.88 | OPRK1 (0.54) | TP53OPRK1UGCGITGB3ITGA2B | |
| SCHEMBL7925240 | 0.88 | UGCG (0.61) | OPRK1UGCGITGB3ITGA2B | |
| SCHEMBL17635995 | 0.88 | UGCG (0.61) | OPRK1UGCGITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039256-A1 | 2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION (US) | 2010-04-08 | — | — | WO | disclosed |