Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8238418 | 0.80 | SIGMAR1 (0.44) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL7925119 | 0.78 | TAAR1 (0.50) | TAAR1MEN1KMT2ASLC6A2SIGMAR1 | |
| SCHEMBL22556238 | 0.76 | TAAR1 (0.50) | TAAR1MEN1KMT2ASLC6A2SIGMAR1 | |
| SCHEMBL8235290 | 0.75 | SIGMAR1 (0.47) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL7864722 | 0.75 | TAAR1 (0.47) | TAAR1MEN1KMT2ASLC6A2SIGMAR1 | |
| SCHEMBL27604048 | 0.74 | TSHR (0.44) | TAAR1MEN1KMT2ACTSB | |
| SCHEMBL5040795 | 0.74 | TAAR1 (0.50) | TAAR1MEN1KMT2ASLC6A2SIGMAR1 | |
| SCHEMBL25209356 | 0.73 | TAAR1 (0.53) | TAAR1MEN1KMT2ASLC6A2SIGMAR1 | |
| SCHEMBL2322253 | 0.73 | CA1 (0.46) | SIGMAR1NPC1RAB9A | |
| SCHEMBL7354997 | 0.73 | TAAR1 (0.53) | TAAR1MEN1KMT2ASLC6A2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2316833-B1 | Process for the preparation of Cyclopamine analogue compounds | INFINITY PHARMACEUTICALS INC (US) | 2016-03-30 | — | — | EP | disclosed |