Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.53 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 3/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16562005 | 0.92 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2TGM2LPAR3LPAR2 | |
| SCHEMBL16562009 | 0.92 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2TGM2LPAR3LPAR2 | |
| SCHEMBL907527 | 0.84 | LPAR3 (0.54) | ZDHHC20ZDHHC2TGM2LPAR3LPAR2 | |
| SCHEMBL16353959 | 0.84 | ZDHHC20 (0.49) | ZDHHC20ZDHHC2TGM2LPAR3LPAR2 | |
| SCHEMBL24359827 | 0.83 | LPAR3 (0.51) | ZDHHC20ZDHHC2TGM2LPAR3LPAR2 | |
| SCHEMBL14996294 | 0.82 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2TGM2ALDH1A1TSHR | |
| SCHEMBL22906226 | 0.81 | CA12 (0.42) | LPAR3LPAR2CA12CA1CA2 | |
| SCHEMBL13750053 | 0.81 | EPHX1 (0.53) | LPAR3LPAR2CA12CA1CA2 | |
| SCHEMBL20041842 | 0.81 | KDM4E (0.53) | LPAR3LPAR2CA12CA1CA2 | |
| SCHEMBL25517756 | 0.81 | KDM4E (0.53) | LPAR3LPAR2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277496-B1 | Dental material containing surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2016-03-30 | — | — | EP | disclosed |