Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.54 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.54 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.54 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24359827 | 0.98 | LPAR3 (0.51) | LPAR3LPAR2ZDHHC20ZDHHC2LPAR1 | |
| SCHEMBL16372096 | 0.93 | LPAR3 (0.49) | LPAR3LPAR2ZDHHC20ZDHHC2LPAR1 | |
| Trimethylammonium SCHEMBL29164957 | 0.87 | ZDHHC20 (0.47) | LPAR3LPAR2ZDHHC20ZDHHC2LPAR1 | |
| SCHEMBL907318 | 0.86 | ALDH1A1 (0.45) | LPAR3LPAR2ZDHHC20ZDHHC2LPAR1 | |
| SCHEMBL17636271 | 0.84 | ZDHHC20 (0.53) | LPAR3LPAR2ZDHHC20ZDHHC2LPAR1 | |
| SCHEMBL16353959 | 0.83 | ZDHHC20 (0.49) | LPAR3LPAR2ZDHHC20ZDHHC2TGM2 | |
| SCHEMBL14996294 | 0.81 | ZDHHC20 (0.65) | ZDHHC20ZDHHC2TGM2ALDH1A1TSHR | |
| SCHEMBL23281607 | 0.80 | ALDH1A1 (0.39) | LPAR3LPAR2ZDHHC20ZDHHC2LPAR1 | |
| SCHEMBL270209 | 0.80 | ZDHHC20 (0.79) | ZDHHC20ZDHHC2TGM2ALDH1A1TSHR | |
| SCHEMBL269468 | 0.80 | ZDHHC20 (0.79) | ZDHHC20ZDHHC2TGM2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10478384-B2 | Dental composition | ZIMMER DENTAL, INC. (US) | 2019-11-19 | — | — | US | claimed |
| EP-2277496-B1 | Dental material containing surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2016-03-30 | — | — | EP | claimed |
| US-20140161901-A1 | DENTAL COMPOSITION | ZIMMER DENTAL, INC. (US) | 2014-06-12 | — | — | US | claimed |
| US-8367748-B2 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2013-02-05 | — | — | US | claimed |
| US-8211956-B2 | Universal dental adhesion-promoter composition | IVOCLAR VIVADENT AG (LI) | 2012-07-03 | — | — | US | claimed |
| US-10478384-B2 | Dental composition | ZIMMER DENTAL, INC. (US) | 2019-11-19 | — | — | US | disclosed |
| EP-2777687-B1 | Dental primer formulation | IVOCLAR VIVADENT AG (LI) | 2018-11-07 | — | — | EP | disclosed |
| US-9974716-B2 | Dental primer formulation | IVOCLAR VIVADENT AG (LI) | 2018-05-22 | — | — | US | disclosed |
| EP-2277496-B1 | Dental material containing surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2016-03-30 | — | — | EP | disclosed |
| US-20160022549-A1 | DENTAL PRIMER FORMULATION | IVOCLAR VIVADENT AG (LI) | 2016-01-28 | — | — | US | disclosed |
| WO-2014139629-A1 | DENTAL PRIMER FORMULATION | IVOCLAR VIVADENT AG (LI) | 2014-09-18 | — | — | WO | disclosed |
| EP-2777687-A1 | Dental primer formulation | Ivoclar Vivadent AG (LI) | 2014-09-17 | — | — | EP | disclosed |
| EP-2277496-A1 | Dental material containing surface-modified fillers | Ivoclar Vivadent AG (LI) | 2011-01-26 | — | — | EP | disclosed |
| EP-1716836-B1 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2011-01-19 | — | — | EP | disclosed |
| US-20100240796-A1 | UNIVERSAL DENTAL ADHESION-PROMOTER COMPOSITION | IVOCLAR VIVADENT AG (LI) | 2010-09-23 | — | — | US | disclosed |
| EP-2229930-A1 | Dental universal adhesive compound | Ivoclar Vivadent AG (LI) | 2010-09-22 | — | — | EP | disclosed |
| US-20090186960-A1 | DENTAL MATERIALS WITH SURFACE-FUNCTIONALIZED FILLERS | IVOCLAR VIVADENT AG (LI) | 2009-07-23 | — | — | US | disclosed |
| EP-2080503-A1 | Dental materials with surface functional fillers | Ivoclar Vivadent AG (LI) | 2009-07-22 | — | — | EP | disclosed |
| EP-1716836-A1 | Surface-modified fillers | Ivoclar Vivadent AG (LI) | 2006-11-02 | — | — | EP | disclosed |
| US-20060247329-A1 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10478384-B2 | Dental composition | CAD, PPIP5K2, PTH1R | LPAR3 2504/4885LPAR2 2896/4885ZDHHC20 4692/4885 |
| US-20160022549-A1 | DENTAL PRIMER FORMULATION | F12, H1-2, H1-0 | LPAR3 962/4885LPAR2 1639/4885ZDHHC20 3431/4885 |
| US-20140161901-A1 | DENTAL COMPOSITION | CAD, PPIP5K2, PTH1R | LPAR3 2504/4885LPAR2 2896/4885ZDHHC20 4692/4885 |
| US-20090186960-A1 | DENTAL MATERIALS WITH SURFACE-FUNCTIONALIZED FILLERS | ITGAM, ITGA5, ITGA1 | LPAR3 3382/4885LPAR2 4458/4885ZDHHC20 3076/4885 |
| US-20060247329-A1 | Surface-modified fillers | MSR1, HRH4, OR10J3 | LPAR3 675/4885LPAR2 2413/4885ZDHHC20 1730/4885 |
| US-20100240796-A1 | UNIVERSAL DENTAL ADHESION-PROMOTER COMPOSITION | CDH1, CAD, CD44 | LPAR3 3081/4885LPAR2 3275/4885ZDHHC20 4064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.