SCHEMBL1763628

SCHEMBL1763628

Cc1cnc(C(N)N)cn1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UHRF1 Q96T88 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29613118 0.83 UHRF1 (0.33) UHRF1
SCHEMBL2339196 0.83 UHRF1 (0.33) UHRF1
SCHEMBL8053862 0.83 UHRF1 (0.33) UHRF1
Hydrochloric Acid SCHEMBL28474927 0.81 UHRF1 (0.32) UHRF1
Hydrochloric Acid SCHEMBL20644229 0.81 UHRF1 (0.32) UHRF1
Hydrochloric Acid SCHEMBL17823742 0.81 UHRF1 (0.32) UHRF1
Hydrochloric Acid SCHEMBL30092204 0.81 UHRF1 (0.32) UHRF1
Hydrochloric Acid SCHEMBL3031125 0.81 UHRF1 (0.32) UHRF1
Hydrochloric Acid SCHEMBL30092129 0.81 UHRF1 (0.32) UHRF1
SCHEMBL179362 0.77 NPC1 (0.36) UHRF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110118186-A1 SYNTHETIC PEPTIDE AMIDES AND DIMERIC FORMS THEREOF CARA THERAPEUTICS, INC. (US) 2011-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110118186-A1 SYNTHETIC PEPTIDE AMIDES AND DIMERIC FORMS THEREOF OPRK1, OPRM1, OPRL1 UHRF1 4783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.