Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922429 | 0.91 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10TSHRCYP3A4 | |
| SCHEMBL18098051 | 0.87 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL1922430 | 0.85 | ALDH1A1 (0.45) | ALDH1A1LMNAHSD17B10TSHRCYP3A4 | |
| SCHEMBL17636252 | 0.83 | LMNA (0.40) | ALDH1A1LMNAHSD17B10TSHRCYP3A4 | |
| SCHEMBL14154035 | 0.81 | LMNA (0.41) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL8277381 | 0.78 | ALDH1A1 (0.54) | ALDH1A1TSHR | |
| SCHEMBL2220993 | 0.76 | ALDH1A1 (0.62) | ALDH1A1TSHR | |
| SCHEMBL6857994 | 0.75 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL14607672 | 0.75 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10TSHR | |
| Nitric Acid SCHEMBL10587822 | 0.73 | ALDH1A1 (0.48) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2329862-B1 | Nitrate esters and their use for the treatment of muscle and muscle related diseases | CHARLOTTE MECKLENBURG HOSPITAL (US) | 2016-03-30 | — | — | EP | disclosed |