Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SORD | Q00796 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19413677 | 0.83 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1SORDTSHRMAPK1 | |
| SCHEMBL19297301 | 0.80 | ESR1 (0.39) | L3MBTL1ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL23020142 | 0.78 | SORD (0.37) | L3MBTL1ALDH1A1SORDTSHRMAPK1 | |
| SCHEMBL30615383 | 0.78 | HTT (0.37) | ALDH1A1HTTKMT2ALMNA | |
| SCHEMBL24381707 | 0.78 | NPC1 (0.40) | L3MBTL1ALDH1A1TSHRHTTKMT2A | |
| SCHEMBL20407213 | 0.77 | MEN1 (0.41) | ALDH1A1TSHRMAPK1KMT2ALMNA | |
| SCHEMBL25859634 | 0.75 | NR1H2 (0.51) | ALDH1A1TSHRHTTKMT2ALMNA | |
| SCHEMBL19450138 | 0.73 | L3MBTL1 (0.35) | L3MBTL1ALDH1A1MAPK1HTTTNKS2 | |
| SCHEMBL23731770 | 0.72 | TSHR (0.32) | L3MBTL1TSHRMAPK1HSD17B10 | |
| SCHEMBL22448126 | 0.72 | L3MBTL1 (0.33) | L3MBTL1TSHRMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016045769-A1 | HETEROCYCLIC COMPOUNDS WITH BENZO[C]COUMARIN-STRUCTURES | MERCK PATENT GMBH (DE) | 2016-03-31 | — | — | WO | disclosed |