Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | REN | P00797 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.46 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17640589 | 0.94 | CTSK (0.51) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL1176795 | 0.92 | CTSL (0.62) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL1026994 | 0.92 | CTSL (0.62) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL1026997 | 0.92 | CTSL (0.62) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL4576576 | 0.89 | CTSL (0.56) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL2632711 | 0.88 | CTSL (0.58) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL24130602 | 0.86 | CTSL (0.60) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL18762521 | 0.86 | CTSL (0.53) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL28948914 | 0.86 | CTSL (0.56) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL26818450 | 0.86 | CTSL (0.56) | CTSLCTSBCTSSCTSKCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016046843-A1 | PROCESS FOR THE PREPARATION OF (S)-4-METHYL-N-((S)-1-(((S)-4-METHYL-1-((R)-2-METHYLOXIRAN-2-YL)-1-OXO PENTAN-2-YL) AMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO) PENTANAMIDE | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2016-03-31 | — | — | WO | disclosed |