Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319704 | 0.82 | MAPT (0.39) | MAPTCYP2C19ALDH1A1 | |
| SCHEMBL13380868 | 0.80 | HSD17B10 (0.62) | HSD17B10TDP1USP2CYP3A4HTT | |
| SCHEMBL12434699 | 0.78 | TSHR (0.56) | HSD17B10TDP1HTTALDH1A1ALOX15 | |
| SCHEMBL4442774 | 0.77 | TSHR (0.42) | TDP1MAPTCYP3A4 | |
| SCHEMBL27544332 | 0.77 | LMNA (0.63) | TDP1MAPTLMNAALDH1A1 | |
| SCHEMBL2228690 | 0.76 | — | — | |
| SCHEMBL27507423 | 0.74 | ACE2 (0.52) | HSD17B10TDP1MAPTUSP2CYP1A2 | |
| Fluoride SCHEMBL28370581 | 0.74 | MAPT (0.52) | MAPTALDH1A1 | |
| SCHEMBL28647763 | 0.73 | ACE2 (0.46) | TDP1MAPTCYP3A4ALDH1A1 | |
| SCHEMBL14528308 | 0.73 | HSD17B10 (0.54) | HSD17B10TDP1USP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016046178-A1 | SILICONE COMPOUNDS AND COMPOSITIONS THEREOF FOR THE TREATMENT OF AMINO ACID BASED SUBSTRATES | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2016-03-31 | — | — | WO | disclosed |