SCHEMBL17642148

SCHEMBL17642148

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(-n6c7ccc8ccccc8c7c7c8ccccc8ccc76)cccc5c4)ccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
PTGES O14684 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
PTGER4 P35408 1/20 0.34
ALDH1A1 P00352 1/20 0.33
HTR6 P50406 2/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
JAK2 O60674 1/20 0.32
JAK3 P52333 1/20 0.32
POLB P06746 1/20 0.31
HSD17B1 P14061 2/20 0.31
HSD17B2 P37059 2/20 0.31
CYP1A2 P05177 2/20 0.31
TSPO P30536 1/20 0.31
HDAC4 P56524 1/20 0.31
ERBB2 P04626 1/20 0.31
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19266515 0.98 KDM4E (0.43) KDM4EATML3MBTL1PTGESTDP1
SCHEMBL19266979 0.94 KDM4E (0.41) KDM4EATML3MBTL1PTGESTDP1
SCHEMBL19266862 0.94 KDM4E (0.42) KDM4EATML3MBTL1TDP1ALDH1A1
SCHEMBL26495881 0.94 KDM4E (0.46) KDM4EATML3MBTL1PTGESTDP1
SCHEMBL19428976 0.93 KDM4E (0.43) KDM4EATML3MBTL1PTGESTDP1
SCHEMBL17642143 0.93 L3MBTL1 (0.45) KDM4EATML3MBTL1PTGESPTGER4
SCHEMBL23862288 0.91 KDM4E (0.46) KDM4EATML3MBTL1PTGESTDP1
SCHEMBL19653519 0.91 KDM4E (0.46) KDM4EATML3MBTL1PTGESTDP1
SCHEMBL23862325 0.91 KDM4E (0.46) KDM4EATML3MBTL1PTGESTDP1
SCHEMBL19267107 0.91 KDM4E (0.46) KDM4EATML3MBTL1PTGESTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10886474-B2 Organic electroluminescent compound, and organic electroluminescent material and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2021-01-05 US disclosed
US-20170294590-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-10-12 US disclosed
US-20170294590-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-10-12 US disclosed
WO-2016048109-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2016-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10886474-B2 Organic electroluminescent compound, and organic electroluminescent material and organic electroluminescent device comprising the same ICOSLG, SOD1, ELAVL1 KDM4E 868/4885ATM 991/4885L3MBTL1 235/4885
US-20170294590-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ICOSLG, SOD1, ELAVL1 KDM4E 868/4885ATM 991/4885L3MBTL1 235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.