Biphenyl

Biphenyl

SCHEMBL1764503

I.O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Biphenyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.82
MAPK1 P28482 2/20 0.53
TAAR1 Q96RJ0 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
HSD17B10 Q99714 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
NOTUM Q6P988 1/20 0.53
MMP3 P08254 1/20 0.53
BCL2L1 Q07817 1/20 0.53
ATM Q13315 1/20 0.47
SLC22A2 O15244 1/20 0.47
SLC22A1 O15245 1/20 0.47
SLC22A3 O75751 1/20 0.47
SLC6A4 P31645 1/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
MAOA P21397 1/20 0.45
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL1157981 0.95 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL29839700 0.95 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL36559 0.95 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL8993020 0.95 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL51203 0.95 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL27966871 0.95 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL27842187 0.95 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL27907683 0.95 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL9634747 0.91 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL1150073 0.91 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1275095-C Novel process for preparing resists CLARIANT INT LTD (JP) 2006-09-13 CN claimed
CN-1239556-A Novel process for preparing resists CLARIANT INT LTD (CH) 1999-12-22 CN claimed
CN-114660896-B Composition for forming silicon-containing resist underlayer film, pattern forming method, and silicon compound 信越化学工业株式会社 2024-06-11 CN disclosed
US-20240085785-A1 ADDITIVES FOR METAL OXIDE PHOTORESISTS, POSITIVE TONE DEVELOPMENT WITH ADDITIVES, AND DOUBLE BAKE DOUBLE DEVELOP PROCESSING JSR CORPORATION (JP) 2024-03-14 US disclosed
WO-2024039626-A1 ADDITIVES FOR METAL OXIDE PHOTORESISTS, POSITIVE TONE DEVELOPMENT WITH ADDITIVES, AND DOUBLE BAKE DOUBLE DEVELOP PROCESSING INPRIA CORPORATION (US) 2024-02-22 WO disclosed
CN-117255971-A Composition for forming silicon-containing resist underlayer film 日产化学株式会社 2023-12-19 CN disclosed
CN-111423587-A Thermosetting silicon-containing compound, composition for forming silicon-containing film, and method for forming pattern 信越化学工业株式会社 2020-07-17 CN disclosed
CN-103025835-B The compositions of coating on photoetching agent pattern 默克专利有限公司 2016-06-29 CN disclosed
CN-101809502-B Thick film resists AZ ELECTRONIC MATERIALS USA 2014-01-08 CN disclosed
CN-103025835-A A composition for coating over a photoresist pattern AZ ELECTRONIC MATERIALS USA 2013-04-03 CN disclosed
US-20110122177-A1 Ink Jet Recording Apparatus KABUSHIKI KAISHA TOSHIBA (JP) 2011-05-26 US disclosed
US-6284427-B1 Process for preparing resists CLARIANT FINANCE (BVI) LIMITED (VG) 2001-09-04 US disclosed
EP-0677788-B1 Radiation-sensitive mixture CLARIANT FINANCE BVI LTD (VG) 2000-06-21 EP disclosed
CN-1239556-A Novel process for preparing resists CLARIANT INT LTD (CH) 1999-12-22 CN disclosed
EP-0942329-A1 NOVEL PROCESS FOR PREPARING RESISTS Clariant International Ltd. (CH) 1999-09-15 EP disclosed
EP-0710885-B1 Radiation sensitive composition CLARIANT FINANCE BVI LTD (VG) 1998-12-30 EP disclosed
US-5738972-A BLEND OF BINDER, DISSOLUTION INHIBITOR, PHOTOSENSITIVR COMPOUND, BASE, PHENOLIC RESIN AND SOLVENT HOECHST JAPAN LIMITED (JP) 1998-04-14 US disclosed
US-5663035-A PHOTOSENSITIVE ACID GENERATORS, PHOTORESISTS, CONTROLLING ACID DIFFUSION WITH IODONIUM COMPOUND HOECHST JAPAN LIMITED (JP) 1997-09-02 US disclosed
EP-0710885-A1 Radiation sensitive composition HOECHST JAPAN LIMITED (JP) 1996-05-08 EP disclosed
EP-0677788-A1 Radiation-sensitive mixture HOECHST JAPAN LIMITED (JP) 1995-10-18 EP disclosed