Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Biphenyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.90 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL1157981 | 1.00 | ALDH1A1 (0.90) | ALDH1A1MAPK1TAAR1CYP1A2CYP3A4 | |
| Biphenyl SCHEMBL29839700 | 1.00 | ALDH1A1 (0.90) | ALDH1A1MAPK1TAAR1CYP1A2CYP3A4 | |
| Biphenyl SCHEMBL1764503 | 0.95 | ALDH1A1 (0.82) | ALDH1A1MAPK1TAAR1CYP1A2CYP3A4 | |
| Biphenyl SCHEMBL27988425 | 0.95 | ALDH1A1 (0.82) | ALDH1A1MAPK1TAAR1CYP1A2CYP3A4 | |
| Biphenyl SCHEMBL10614964 | 0.95 | ALDH1A1 (0.82) | ALDH1A1MAPK1TAAR1CYP1A2CYP3A4 | |
| Biphenyl SCHEMBL8979596 | 0.95 | ALDH1A1 (0.82) | ALDH1A1MAPK1TAAR1CYP1A2CYP3A4 | |
| Biphenyl SCHEMBL9634747 | 0.95 | ALDH1A1 (0.82) | ALDH1A1MAPK1TAAR1CYP1A2CYP3A4 | |
| Biphenyl SCHEMBL1150073 | 0.95 | ALDH1A1 (0.82) | ALDH1A1MAPK1TAAR1CYP1A2CYP3A4 | |
| Biphenyl SCHEMBL1069729 | 0.95 | ALDH1A1 (0.82) | ALDH1A1MAPK1TAAR1CYP1A2CYP3A4 | |
| Biphenyl SCHEMBL164 | 0.95 | ALDH1A1 (1.00) | ALDH1A1MAPK1TAAR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2042 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260029711-A1 | ENHANCED EUV MATERIALS, PHOTORESISTS AND METHODS OF THEIR USE. | IRRESISTIBLE MATERIALS LTD (GB) | 2026-01-29 | — | — | US | claimed |
| US-20250314969-A1 | SELF-ALIGNED DOUBLE PATTERNING USING METAL-BASED RESIST | TOKYO ELECTRON LTD (JP) | 2025-10-09 | — | — | US | claimed |
| CN-118666940-A | Double bond arylation modification method | 深圳先进技术研究院 | 2024-09-20 | — | — | CN | claimed |
| CN-114589021-B | Method and device for preparing photo-thermal curing electrostatic spray film | 温州理工学院 | 2024-08-30 | — | — | CN | claimed |
| EP-4370564-A1 | COMPOSITION BASED ON (METH)ACRYLATE MONOMERS | Bostik SA (FR) | 2024-05-22 | — | — | EP | claimed |
| EP-4370563-A1 | COMPOSITION BASED ON (METH)ACRYLATE MONOMERS | Bostik SA (FR) | 2024-05-22 | — | — | EP | claimed |
| CN-111094385-B | Charge-transporting compound, composition containing charge-transporting compound, and organic electroluminescent element using same | 三菱化学株式会社 | 2024-04-09 | — | — | CN | claimed |
| CN-116836107-B | Carbazol eight-membered ring large conjugated structure OLED material and preparation method thereof | 西安欧得光电材料有限公司 | 2024-02-27 | — | — | CN | claimed |
| WO-2024010706-A1 | ENHANCED EUV MATERIALS, PHOTORESISTS AND METHODS OF THEIR USE | ROBINSON ALEX P G (GB) | 2024-01-11 | — | — | WO | claimed |
| CN-117304542-A | Acrylate hardening film for mobile phone folding screen and preparation method thereof | 张家港泰恩半导体材料有限公司 | 2023-12-29 | — | — | CN | claimed |
| US-5488026-A | Thermal dye transfer system with receiver containing an acid-generating compound | EASTMAN KODAK COMPANY (US) | 1996-01-30 | — | — | US | claimed |
| US-5334699-A | Polymeric initiator compounds | XEROX CORPORATION (US) | 1994-08-02 | — | — | US | claimed |
| EP-0298030-B1 | PROCESS FOR FORMING IMAGES | CIBA-GEIGY AG (CH) | 1992-10-28 | — | — | EP | claimed |
| US-5140054-A | Heat and chemical resistance, adhesive, colorless, durable film used as a protective coating | ISP INVESTMENTS INC. (US) | 1992-08-18 | — | — | US | claimed |
| US-4978604-A | Process for forming images | CIBA-GEIGY CORPORATION (US) | 1990-12-18 | — | — | US | claimed |
| US-4968581-A | High resolution photoresist of imide containing polymers | HOECHST CELANESE CORPORATION (US) | 1990-11-06 | — | — | US | claimed |
| US-4912018-A | High resolution photoresist based on imide containing polymers | HOECHST CELANESE CORPORATION (US) | 1990-03-27 | — | — | US | claimed |
| CN-1032807-A | The Photocurable composition that contains the ionic dyes complex compound of photochromic (photobleaching) | MEAD CORP (US) | 1989-05-10 | — | — | CN | claimed |
| EP-0298030-A2 | Process for forming images | CIBA-GEIGY AG (CH) | 1989-01-04 | — | — | EP | claimed |
| US-4383903-A | POLYFUNCTIONAL AROMATIC CYANATE, ACRYLIC COMPOUND, POLYFUNCTIONAL MALEIMIDE, PHOTOINITIATOR | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1983-05-17 | — | — | US | claimed |