SCHEMBL1764748

SCHEMBL1764748

NC1CCC2CCCCC2C1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
THRB P10828 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALOX5 P09917 1/20 0.31
OPRM1 P35372 1/20 0.30
OPRK1 P41145 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12555016 1.00 ALDH1A1 (0.47) ALDH1A1THRBMEN1KMT2AALOX5
SCHEMBL9359595 1.00 ALDH1A1 (0.47) ALDH1A1THRBMEN1KMT2AALOX5
SCHEMBL9887510 1.00 ALDH1A1 (0.47) ALDH1A1THRBMEN1KMT2AALOX5
SCHEMBL9886936 1.00 ALDH1A1 (0.47) ALDH1A1THRBMEN1KMT2AALOX5
SCHEMBL24170123 0.97 ALDH1A1 (0.44) ALDH1A1THRBMEN1KMT2A
SCHEMBL12540471 0.97 ALDH1A1 (0.44) ALDH1A1THRBMEN1KMT2A
SCHEMBL12689882 0.97 ALDH1A1 (0.44) ALDH1A1THRBMEN1KMT2A
SCHEMBL3844589 0.94 ALDH1A1 (0.39) ALDH1A1
SCHEMBL16512832 0.94 ALDH1A1 (0.39) ALDH1A1
SCHEMBL18506484 0.94 ALDH1A1 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116496164-A Method for synthesizing chain polyamine compound by monoprimary amine 湖北领固材料技术有限公司 2023-07-28 CN claimed
CN-114621259-A Metal organic hydride complex material and preparation method and application thereof 中国科学院大连化学物理研究所 2022-06-14 CN claimed
CN-112961097-A Preparation method and application of organic metal compound 中国科学院大连化学物理研究所 2021-06-15 CN claimed
CN-112250582-A Preparation method of amino metal compound and application of amino metal compound 中国科学院大连化学物理研究所 2021-01-22 CN claimed
EP-0369335-B1 2-Aminodecaline derivatives and their use BASF AG (DE) 1994-02-23 EP claimed
US-5051409-A Fungicides BASF AKTIENGESELLSCHAFT (DE) 1991-09-24 US claimed
CN-113677334-B Transient receptor potential MELASTATIN 8 (TRPM 8) antagonists and related methods 马歇尔大学科研协会 2024-04-09 CN disclosed
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 C4 THERAPEUTICS, INC. (US) 2023-10-26 US disclosed
CN-116496164-A Method for synthesizing chain polyamine compound by monoprimary amine 湖北领固材料技术有限公司 2023-07-28 CN disclosed
CN-116496164-A Method for synthesizing chain polyamine compound by monoprimary amine 湖北领固材料技术有限公司 2023-07-28 CN disclosed
WO-2023277605-A1 NOVEL COMPOUND FOR CAPPING LAYER AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 동진쎄미켐 2023-01-05 WO disclosed
WO-2023277594-A1 NOVEL COMPOUND FOR CAPPING LAYER, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 동진쎄미켐 2023-01-05 WO disclosed
US-20220313629-A1 TRANSIENT POTENTIAL MELASTATIN 8 (TRPM8) ANTAGONISTS AND RELATED METHODS MARSHALL UNIVERSITY RESEARCH CORPORATION 2022-10-06 US disclosed
EP-0355544-A2 Substituted decalin amines, method for their preparation and their use in pesticides BAYER AG (DE) 1990-02-28 EP disclosed
WO-1989000563-A1 HIGH POTENCY SWEETENING AGENTS THE NUTRASWEET COMPANY (US) 1989-01-26 WO disclosed
EP-0299533-A2 High potency sweetening agents THE NUTRASWEET COMPANY (a Delaware corporation) (US) 1989-01-18 EP disclosed
EP-0171847-B1 LIQUID, CURABLE COATING COMPOSITION BASED ON A HYDROXYL GROUPS-CONTAINING ADDITION POLYMER AS BINDER AKZO N.V. (NL) 1988-06-01 EP disclosed
US-4605719-A ISOBORNYL ACKYLATE AND MONO-ETHYLENICALLY UNSATURATED POLYCYCLIC CYCLIC COMPOUNDS; PROTECTIVE COATINGS AKZO NV (NL) 1986-08-12 US disclosed
EP-0171847-A1 Liquid, curable coating composition based on a hydroxyl groups-containing addition polymer as binder AKZO N.V. (NL) 1986-02-19 EP disclosed
US-3969365-A ANTIINFLAMMATORY, HYPOGLYCEMIC E. R. SQUIBB & SONS, INC. (US) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 IKZF1, IKZF3, IKZF2 ALDH1A1 4344/4885THRB 2062/4885MEN1 3335/4885
US-20220313629-A1 TRANSIENT POTENTIAL MELASTATIN 8 (TRPM8) ANTAGONISTS AND RELATED METHODS TRPM8, TRPV1, TRPM7 ALDH1A1 2851/4885THRB 563/4885MEN1 1452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.