⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10420443 | 0.98 | — | — | |
| SCHEMBL23397118 | 0.83 | MMP1 (0.31) | — | |
| SCHEMBL23397101 | 0.77 | MMP1 (0.30) | — | |
| SCHEMBL21510160 | 0.76 | — | — | |
| SCHEMBL10748897 | 0.76 | CYP1A2 (0.37) | — | |
| SCHEMBL1133019 | 0.75 | SLC6A4 (0.34) | — | |
| SCHEMBL498649 | 0.74 | L3MBTL1 (0.32) | — | |
| SCHEMBL8508591 | 0.74 | — | — | |
| SCHEMBL22685893 | 0.74 | — | — | |
| SCHEMBL1660684 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2504324-B1 | SULTAM DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2015-02-25 | — | — | EP | disclosed |
| US-8314250-B2 | Sultam derivatives | HOFFMANN-LA ROCHE INC. (US) | 2012-11-20 | — | — | US | disclosed |
| US-20110124686-A1 | SULTAM DERIVATIVES | ANDERSON KEVIN W | 2011-05-26 | — | — | US | disclosed |
| EP-0436435-B1 | Phenylethanolaminomethyltetralins, procedure for their preparation and pharmaceutical compositions containing same | SANOFI ELF (FR) | 1994-03-23 | — | — | EP | disclosed |
| US-5130339-A | Intestine and uterine motility modulators for reduction of intraocular pressure for glaucoma treatment | SANOFI (FR) | 1992-07-14 | — | — | US | disclosed |
| EP-0436435-A1 | Phenylethanolaminomethyltetralins, procedure for their preparation and pharmaceutical compositions containing same | ELF SANOFI (FR) | 1991-07-10 | — | — | EP | disclosed |
| EP-0282770-B1 | OPTICALLY ACTIVE (METH)-ACRYLAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE SEPARATION OF RACEMATES | BAYER AG (DE) | 1990-06-27 | — | — | EP | disclosed |
| US-4937000-A | SILICA-IMMOBILIZED HOMO-AND COPOLYMERS; ADSORBENTS FOR CHROMA TOGRAPHIC SEDARATION | BAYER AKTIENGESELLSCHAFT (DE) | 1990-06-26 | — | — | US | disclosed |
| US-4914159-A | Optically active (meth)acrylamides, a process for their preparation, and their use for racemate resolution | BAYER AKTIENGESELLSCHAFT (DE) | 1990-04-03 | — | — | US | disclosed |
| EP-0282770-A1 | Optically active (meth)-acrylamides, process for their preparation and their use in the separation of racemates | BAYER AG (DE) | 1988-09-21 | — | — | EP | disclosed |
| EP-0218089-B1 | OPTICALLY ACTIVE (METH)-ACRYL AMIDE, POLYMERS THEREOF, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE SEPARATION OF RACEMATES | BAYER AG (DE) | 1988-06-22 | — | — | EP | disclosed |
| EP-0218089-A1 | Optically active (meth)-acryl amide, polymers thereof, process for their preparation and their use in the separation of racemates | BAYER AG (DE) | 1987-04-15 | — | — | EP | disclosed |