Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 2/20 | 0.59 |
| ▸ | RPA1 | P27694 | 12/20 | 0.57 |
| ▸ | PPP1CA | P62136 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110689 | 0.90 | PPP1CA (0.64) | MARS1RPA1PPP1CASMN1; SMN2 | |
| SCHEMBL16921447 | 0.89 | RPA1 (0.58) | MARS1RPA1PPP1CAMEN1KMT2A | |
| SCHEMBL16910537 | 0.89 | MARS1 (0.60) | MARS1RPA1PPP1CAMEN1KMT2A | |
| SCHEMBL12597093 | 0.88 | MARS1 (0.59) | MARS1RPA1PPP1CAMEN1KMT2A | |
| SCHEMBL1764873 | 0.88 | RPA1 (0.64) | MARS1RPA1PPP1CAMEN1KMT2A | |
| SCHEMBL1764962 | 0.88 | FAAH (0.55) | MARS1RPA1 | |
| SCHEMBL15004289 | 0.87 | MARS1 (0.58) | MARS1RPA1PPP1CAMEN1KMT2A | |
| SCHEMBL16910546 | 0.86 | MARS1 (0.57) | MARS1RPA1PPP1CAMEN1KMT2A | |
| SCHEMBL16921424 | 0.86 | RPA1 (0.59) | MARS1RPA1PPP1CAMEN1KMT2A | |
| SCHEMBL3425400 | 0.86 | SLC5A1 (0.46) | MARS1RPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399682-B2 | Substituted (pyrazolylcarbonyl)imidazolidinones and their use | AICURIS GMBH & CO. KG (DE) | 2013-03-19 | — | — | US | disclosed |
| US-8399682-B2 | Substituted (pyrazolylcarbonyl)imidazolidinones and their use | AICURIS GMBH & CO. KG (DE) | 2013-03-19 | — | — | US | disclosed |
| US-8399682-B2 | Substituted (pyrazolylcarbonyl)imidazolidinones and their use | AICURIS GMBH & CO. KG (DE) | 2013-03-19 | — | — | US | disclosed |
| US-20110124618-A1 | SUBSTITUTED (PYRAZOLYLCARBONYL)IMIDAZOLIDINONES AND THEIR USE | AICURIS GMBH & CO. KG (DE) | 2011-05-26 | — | — | US | disclosed |
| CN-101977908-A | (pyrazolyl carbonyl) imidazolidinone derivatives for the treatment of retroviral diseases | AICURIS GMBH & CO KG | 2011-02-16 | — | — | CN | disclosed |
| WO-2009115213-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AICURIS GMBH & CO. KG (DE) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124618-A1 | SUBSTITUTED (PYRAZOLYLCARBONYL)IMIDAZOLIDINONES AND THEIR USE | TPMT, PAICS, THPO | MARS1 1601/4885RPA1 3978/4885PPP1CA 1664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.