Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711185 | 0.93 | TSHR (0.58) | TSHRALDH1A1MEN1LMNATHRB | |
| Benzaldehyde SCHEMBL28137222 | 0.90 | ALDH1A1 (0.55) | TSHRALDH1A1MEN1LMNATHRB | |
| SCHEMBL3932855 | 0.85 | ALDH1A1 (0.59) | TSHRALDH1A1MEN1LMNATHRB | |
| SCHEMBL1830923 | 0.85 | ALDH1A1 (0.59) | TSHRALDH1A1MEN1LMNATHRB | |
| SCHEMBL30340593 | 0.85 | ALDH1A1 (0.59) | TSHRALDH1A1MEN1LMNATHRB | |
| SCHEMBL31175932 | 0.85 | KMT2A (0.71) | TSHRALDH1A1MEN1LMNATHRB | |
| SCHEMBL249552 | 0.85 | KMT2A (0.71) | TSHRALDH1A1MEN1LMNATHRB | |
| SCHEMBL29186211 | 0.84 | ALDH1A1 (0.57) | TSHRALDH1A1MEN1LMNATHRB | |
| SCHEMBL1669198 | 0.84 | ALDH1A1 (0.57) | TSHRALDH1A1MEN1LMNATHRB | |
| SCHEMBL1666568 | 0.84 | ALDH1A1 (0.57) | TSHRALDH1A1MEN1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114082446-B | Chiral zirconium catalyst for preparing chiral alpha-hydroxy-beta-keto ester compound and preparation method thereof | 南开沧州渤海新区绿色化工研究有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-114082446-A | Chiral zirconium catalyst for preparing chiral alpha-hydroxy-beta-keto ester compound and preparation method thereof | 南开沧州渤海新区绿色化工研究有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-106660971-B | Dual inhibitor compounds for use in the treatment of neurodegenerative diseases and alzheimer's disease | 意大利学院科技基金会 | 2020-10-13 | — | — | CN | disclosed |
| US-10351506-B2 | Purified plasticizers, production and use | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2019-07-16 | — | — | US | disclosed |
| US-20190031593-A1 | Purified Plasticizers, Production and Use | EXXONMOBIL CHEMICAL PATENTS INC. | 2019-01-31 | — | — | US | disclosed |
| US-9944618-B2 | Inhibiting neurotransmitter reuptake | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2018-04-17 | — | — | US | disclosed |
| US-20160024044-A1 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2016-01-28 | — | — | US | disclosed |
| EP-2504324-B1 | SULTAM DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2015-02-25 | — | — | EP | disclosed |
| US-8883796-B2 | Biphenyl derivatives, pharmaceutical composition comprising the same, and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-11-11 | — | — | US | disclosed |
| WO-2014159251-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2014-10-02 | — | — | WO | disclosed |
| EP-0239423-B1 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1996-03-20 | — | — | EP | disclosed |
| EP-0342635-B1 | Azacyclic carboxylic acid derivatives, their preparation and use | NOVO NORDISK AS (DK) | 1994-08-17 | — | — | EP | disclosed |
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| CN-1055927-A | Benzimidazole derivatives, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1991-11-06 | — | — | CN | disclosed |
| US-5019479-A | Photoresists for integrated circuits | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-28 | — | — | US | disclosed |
| EP-0342635-A1 | Azacyclic carboxylic acid derivatives, their preparation and use | NOVO NORDISK A/S (DK) | 1989-11-23 | — | — | EP | disclosed |
| EP-0239423-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-09-30 | — | — | EP | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |
| US-4192824-A | CARBONYL COMPOUNDS PROVIDE RING CLOSURE OF POLYCYCLIC COMPOUNDS | COAL INDUSTRY (PATENTS) LIMITED (GB) | 1980-03-11 | — | — | US | disclosed |
| US-4137259-A | SILVER VANADATE, IRON VANADATE | STAMICARBON, B.V. (NL) | 1979-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351506-B2 | Purified plasticizers, production and use | ALKBH3, FTO, ALK | TSHR 2624/4885ALDH1A1 142/4885MEN1 3330/4885 |
| US-20190031593-A1 | Purified Plasticizers, Production and Use | ALKBH3, FTO, ALK | TSHR 2624/4885ALDH1A1 142/4885MEN1 3330/4885 |
| US-20160024044-A1 | INHIBITING NEUROTRANSMITTER REUPTAKE | SLC6A2, SLC18A2, SLC6A4 | TSHR 652/4885ALDH1A1 173/4885MEN1 880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.