SCHEMBL1765232

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27344645	0.90	KIF11 (0.63)	KIF11KDM4EKDM1AMAOBKMT2A
	SCHEMBL1765328	0.89	KIF11 (0.59)	KIF11NPC1RAB9ASMN1; SMN2GFER
	SCHEMBL29690424	0.88	KIF11 (0.61)	KIF11KDM4EKDM1AMAOBKMT2A
	SCHEMBL28530523	0.88	KIF11 (0.61)	KIF11KDM4EKDM1AMAOBKMT2A
	SCHEMBL4342508	0.86	KIF11 (0.59)	KIF11KDM4EKDM1AMAOBKMT2A
	SCHEMBL556994	0.83	KIF11 (0.56)	KIF11NPC1RAB9ASMN1; SMN2KDM4E
	SCHEMBL3392514	0.81	KIF11 (0.55)	KIF11KDM4EKDM1AMAOBKMT2A
	SCHEMBL28403735	0.81	KIF11 (0.55)	KIF11NPC1RAB9ASMN1; SMN2KDM4E
	SCHEMBL29164328	0.81	KIF11 (0.55)	KIF11KDM4EALDH1A1KDM1AMAOB
	SCHEMBL8192167	0.81	KIF11 (0.55)	KIF11KDM4EALDH1A1POLBKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.