Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | CFTR | P13569 | 2/20 | 0.33 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2537360 | 0.77 | ALDH1A1 (0.36) | ALDH1A1KDM1AMAOBRAB9A | |
| SCHEMBL145371 | 0.74 | MAOB (0.44) | ALDH1A1KDM1AMAOBCYP1A2LMNA | |
| SCHEMBL2013779 | 0.74 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL9130854 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KDM1AMAOBRAB9AMAOA | |
| SCHEMBL695560 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KDM1ACFTRGOPCMAPK1 | |
| SCHEMBL14974371 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KDM1ACFTRGOPCMAPK1 | |
| SCHEMBL28431861 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KDM1AMAOBRAB9AMAOA | |
| SCHEMBL14697788 | 0.70 | MAOB (0.35) | ALDH1A1MAOBLMNAMAPTMAOA | |
| SCHEMBL1224368 | 0.69 | CFTR (0.48) | ALDH1A1KDM1ACFTRGOPCMAOB | |
| Biphenyl SCHEMBL9388941 | 0.64 | ALDH1A1 (0.82) | ALDH1A1MAPK1NPC1RAB9AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3201235-A1 | ANTIBODIES TO TICAGRELOR AND METHODS OF USE | Medimmune Limited (GB) | 2017-08-09 | — | — | EP | disclosed |
| WO-2016050867-A1 | ANTIBODIES TO TICAGRELOR AND METHODS OF USE | MEDIMMUNE LIMITED (GB) | 2016-04-07 | — | — | WO | disclosed |