Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CCR5 | P51681 | 4/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17653262 | 0.88 | KMT2A (0.49) | KMT2AGAAMAPTMAPK1MEN1 | |
| SCHEMBL17653277 | 0.81 | KMT2A (0.51) | KMT2AGAALMNAMAPTMEN1 | |
| SCHEMBL17653363 | 0.80 | GAA (0.56) | KMT2ACCR5GAALMNAMAPT | |
| SCHEMBL17653354 | 0.73 | GAA (0.50) | KMT2AGAAKDM4ELMNAMAPT | |
| SCHEMBL17653325 | 0.73 | GAA (0.58) | KMT2AGAAKDM4ELMNAMAPT | |
| SCHEMBL17653370 | 0.72 | GAA (0.69) | KMT2ACCR5GAAKDM4ELMNA | |
| SCHEMBL17653244 | 0.68 | CCR5 (0.53) | KMT2ACCR5LRRK2PTPN1MEN1 | |
| SCHEMBL20772468 | 0.68 | CTSV (0.61) | KMT2AKDM4EALDH1A1MEN1L3MBTL1 | |
| Hydrogen Sulfide SCHEMBL24697572 | 0.68 | CCR5 (0.52) | CCR5SLC6A4LRRK2LMNAALDH1A1 | |
| SCHEMBL22160850 | 0.68 | MAPK13 (0.44) | KMT2AGAAKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10112895-B2 | Antivirals against molluscum contagiosum virus | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-10-30 | — | — | US | claimed |
| EP-3200778-A1 | ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS | The Trustees Of The University Of Pennsylvania (US) | 2017-08-09 | — | — | EP | claimed |
| US-20170217882-A1 | ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2017-08-03 | — | — | US | claimed |
| WO-2016053893-A1 | ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-04-07 | — | — | WO | claimed |
| US-10112895-B2 | Antivirals against molluscum contagiosum virus | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-10-30 | — | — | US | disclosed |
| EP-3200778-A1 | ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS | The Trustees Of The University Of Pennsylvania (US) | 2017-08-09 | — | — | EP | disclosed |
| US-20170217882-A1 | ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2017-08-03 | — | — | US | disclosed |
| WO-2016053893-A1 | ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10112895-B2 | Antivirals against molluscum contagiosum virus | EIF2AK2, IRF3, ZC3HAV1 | KMT2A 2273/4885CCR5 1579/4885SLC6A4 1921/4885 |
| US-20170217882-A1 | ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS | EIF2AK2, IRF3, ZC3HAV1 | KMT2A 2273/4885CCR5 1579/4885SLC6A4 1921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.