Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 7/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 4/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.59 |
| ▸ | HTR1A | P08908 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4443786 | 0.89 | HTR7 (0.61) | HTR7KCNH2DRD2HTR1A | |
| SCHEMBL7737516 | 0.89 | HTR7 (0.58) | HTR7DRD2 | |
| SCHEMBL4932045 | 0.82 | DPP7 (0.58) | HTR7SIGMAR1 | |
| SCHEMBL9041083 | 0.81 | KCNH2 (0.80) | HTR7KCNH2DRD2SIGMAR1HTR1A | |
| SCHEMBL5549334 | 0.81 | MEN1 (0.68) | KCNH2SIGMAR1CYP2D6 | |
| SCHEMBL9474438 | 0.81 | HTR7 (0.55) | HTR7KCNH2CHRNA7 | |
| Hydrochloric Acid SCHEMBL5753957 | 0.80 | DPP7 (0.56) | HTR7SIGMAR1 | |
| SCHEMBL8673780 | 0.80 | POLB (0.59) | SIGMAR1 | |
| SCHEMBL10733030 | 0.79 | MAPT (0.67) | HTR7HTR1ACYP2D6 | |
| Hydrochloric Acid SCHEMBL11093613 | 0.79 | POLB (0.58) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3201178-A1 | ARYLALKYLPIPERAZINES FOR USE AS NEUROPROTECTIVE AGENTS | University of Hertfordshire Higher Education Corporation (GB) | 2017-08-09 | — | — | EP | disclosed |
| WO-2016051155-A1 | ARYLALKYLPIPERAZINES FOR USE AS NEUROPROTECTIVE AGENTS | UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION (GB) | 2016-04-07 | — | — | WO | disclosed |