Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.61 |
| ▸ | HRH1 | P35367 | 3/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.58 |
| ▸ | HRH2 | P25021 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 5/20 | 0.51 |
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17654095 | 0.89 | HTR7 (0.74) | HTR7DRD2HTR1AKCNH2 | |
| SCHEMBL14409559 | 0.82 | CYP3A4 (0.46) | HTR7HRH1HRH3DRD2 | |
| SCHEMBL7737516 | 0.82 | HTR7 (0.58) | HTR7DRD2DRD3 | |
| SCHEMBL8636247 | 0.80 | DPP7 (0.61) | HRH1HRH3HRH2DRD2HTR1A | |
| SCHEMBL10118660 | 0.78 | DRD2 (0.51) | HRH1HRH3HRH2DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL27908881 | 0.76 | DRD2 (0.72) | DRD2 | |
| SCHEMBL2127950 | 0.76 | HRH3 (0.55) | HRH3DRD3 | |
| SCHEMBL4932045 | 0.76 | DPP7 (0.58) | HTR7DRD3 | |
| SCHEMBL8010491 | 0.75 | DRD2 (0.60) | HTR7HRH1DRD2HTR1ADRD3 | |
| SCHEMBL6671580 | 0.75 | CYP3A4 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074083-A1 | NEW SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | Richter Gedeon NYRT (HU) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050168-A1 | NEW SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2008-05-02 | — | — | WO | disclosed |