Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 11/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.57 |
| ▸ | BCL2 | P10415 | 4/20 | 0.57 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17655014 | 0.90 | BCL2 (0.65) | ADAMTS5MEN1KMT2ABCL2BCL2L1 | |
| SCHEMBL15709086 | 0.84 | MEN1 (0.60) | ADAMTS5MEN1KMT2ABCL2BCL2L1 | |
| SCHEMBL15709085 | 0.84 | MEN1 (0.60) | ADAMTS5MEN1KMT2ABCL2BCL2L1 | |
| SCHEMBL17655012 | 0.83 | ADAMTS5 (0.61) | ADAMTS5MEN1KMT2ABCL2BCL2L1 | |
| SCHEMBL17655015 | 0.83 | MEN1 (0.55) | ADAMTS5MEN1KMT2ABCL2BCL2L1 | |
| SCHEMBL15731851 | 0.81 | MEN1 (0.56) | ADAMTS5MEN1KMT2AATMMAPT | |
| SCHEMBL17655016 | 0.81 | BCL2 (0.62) | ADAMTS5MEN1KMT2ABCL2BCL2L1 | |
| SCHEMBL5970104 | 0.81 | BCL2 (0.80) | ADAMTS5MEN1KMT2ABCL2BCL2L1 | |
| SCHEMBL5970105 | 0.81 | BCL2 (0.80) | ADAMTS5MEN1KMT2ABCL2BCL2L1 | |
| SCHEMBL13219035 | 0.79 | BCL2 (0.67) | ADAMTS5MEN1KMT2ABCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9301940-B2 | Methods for screening antimicrobial and antiviral compounds and uses thereof | THE GENERAL HOSPITAL CORPORATION (US) | 2016-04-05 | — | — | US | disclosed |
| US-9301940-B2 | Methods for screening antimicrobial and antiviral compounds and uses thereof | THE GENERAL HOSPITAL CORPORATION (US) | 2016-04-05 | — | — | US | disclosed |