Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.65 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.54 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17655010 | 0.90 | ADAMTS5 (0.59) | BCL2MEN1KMT2ABCL2L1MCL1 | |
| SCHEMBL5970105 | 0.90 | BCL2 (0.80) | BCL2MEN1KMT2ABCL2L1MCL1 | |
| SCHEMBL5970104 | 0.90 | BCL2 (0.80) | BCL2MEN1KMT2ABCL2L1MCL1 | |
| SCHEMBL13219035 | 0.89 | BCL2 (0.67) | BCL2MEN1KMT2ABCL2L1MCL1 | |
| SCHEMBL17655016 | 0.87 | BCL2 (0.62) | BCL2MEN1KMT2ABCL2L1MCL1 | |
| SCHEMBL17655011 | 0.86 | MEN1 (0.53) | BCL2MEN1KMT2ABCL2L1MCL1 | |
| SCHEMBL17655013 | 0.85 | BCL2 (0.60) | BCL2MEN1KMT2ABCL2L1MCL1 | |
| SCHEMBL17655012 | 0.84 | ADAMTS5 (0.61) | BCL2MEN1KMT2ABCL2L1MCL1 | |
| SCHEMBL17655015 | 0.83 | MEN1 (0.55) | BCL2MEN1KMT2ABCL2L1MCL1 | |
| SCHEMBL13657863 | 0.83 | BCL2 (0.77) | BCL2MEN1KMT2ABCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9301940-B2 | Methods for screening antimicrobial and antiviral compounds and uses thereof | THE GENERAL HOSPITAL CORPORATION (US) | 2016-04-05 | — | — | US | disclosed |
| US-9301940-B2 | Methods for screening antimicrobial and antiviral compounds and uses thereof | THE GENERAL HOSPITAL CORPORATION (US) | 2016-04-05 | — | — | US | disclosed |