Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 10/20 | 0.69 |
| ▸ | CSNK2A1 | P68400 | 10/20 | 0.69 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.69 |
| ▸ | RARA | P10276 | 1/20 | 0.59 |
| ▸ | RARB | P10826 | 1/20 | 0.59 |
| ▸ | RARG | P13631 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14646221 | 0.94 | CSNK2A2 (0.76) | CSNK2A2CSNK2A1CSNK2BNR1H4 | |
| SCHEMBL11599027 | 0.94 | CSNK2A2 (0.76) | CSNK2A2CSNK2A1CSNK2BNR1H4 | |
| SCHEMBL7312799 | 0.87 | CSNK2A2 (0.67) | CSNK2A2CSNK2A1CSNK2BNR1H4 | |
| SCHEMBL11524489 | 0.85 | CSNK2A2 (0.51) | CSNK2A2CSNK2A1CSNK2BRARARARB | |
| SCHEMBL4261162 | 0.84 | CSNK2A2 (0.55) | CSNK2A2CSNK2A1CSNK2BKDM4ENPC1 | |
| SCHEMBL11808344 | 0.83 | CSNK2A2 (0.53) | CSNK2A2CSNK2A1CSNK2BRARARARB | |
| SCHEMBL7322182 | 0.82 | NR1H4 (0.66) | CSNK2A2CSNK2A1CSNK2BRARBNR1H4 | |
| SCHEMBL6538522 | 0.82 | NR1H4 (0.66) | CSNK2A2CSNK2A1CSNK2BRARBNR1H4 | |
| SCHEMBL7324357 | 0.81 | CSNK2A1 (1.00) | CSNK2A2CSNK2A1CSNK2BKDM4ENPC1 | |
| SCHEMBL16991044 | 0.81 | CSNK2A2 (0.65) | CSNK2A2CSNK2A1CSNK2BRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1815206-B1 | COMPOUNDS FOR NONSENSE SUPPRESSION, AND METHODS FOR THEIR USE | PTC THERAPEUTICS INC (US) | 2016-04-06 | — | — | EP | disclosed |