SCHEMBL1765776

SCHEMBL1765776

CC(C)C1=CCC(C)(C)CC1=O

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGES O14684 1/20 0.35
ALOX5 P09917 1/20 0.35
ALDH1A1 P00352 6/20 0.34
PTPN1 P18031 1/20 0.34
HTT P42858 1/20 0.33
MAOA P21397 1/20 0.32
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
CES1 P23141 2/20 0.32
MAPT P10636 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
KDM5B Q9UGL1 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16572379 0.71 HSD11B1 (0.38) ALDH1A1HTTMAOAKDM4EMEN1
SCHEMBL2318962 0.70 ALDH1A1 (0.42) PTGESALOX5ALDH1A1HTTMAOA
SCHEMBL11616927 0.70 ALDH1A1 (0.42) ALDH1A1HTTMAOAKDM4EMEN1
SCHEMBL11618552 0.70 ALDH1A1 (0.36) ALDH1A1HTTMAOAKDM4EMEN1
SCHEMBL10448766 0.67 ALDH1A1 (0.37) PTGESALOX5ALDH1A1MAPT
SCHEMBL4148665 0.67 ALDH1A1 (0.36) ALDH1A1HTTMAOAKDM4EMEN1
SCHEMBL4580954 0.67 GAA (0.43) ALDH1A1HTTMAOAKDM4EMEN1
SCHEMBL15418543 0.67 HSD17B10 (0.35) ALDH1A1HTTMAOAKDM4EMEN1
SCHEMBL1044726 0.66
SCHEMBL10932007 0.65 ALDH1A1 (0.33) ALDH1A1HTTMAOAKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9005679-B2 Use of extracts of Capraria biflora in the prevention and/or treatment of senile cataracts BURROWS ENTERPRISES, LLC (US) 2015-04-14 US disclosed
US-20140370135-A1 USE OF EXTRACTS OF CAPRARIA BIFLORA IN THE PREVENTION AND/OR TREATMENT OF SENILE CATARACTS BURROWS ENTERPRISES, LLC (US) 2014-12-18 US disclosed
US-20130196010-A1 Use of Extracts of Capraria Biflora in the Prevention and/or Treatment of Senile Cataracts BURROWS ENTERPRISES, LLC (US) 2013-08-01 US disclosed
US-20110123647-A1 USE OF EXTRACTS OF CAPRARIA BIFLORA IN THE PREVENTION AND/OR TREATMENT OF SENILE CATARACTS BURROWS ENTERPRISES 2011-05-26 US disclosed
US-7906157-B2 Use of extracts of Capraria biflora in the prevention and/or treatment of senile cataracts BURROWS ENTERPRISES, LLC (US) 2011-03-15 US disclosed
US-20090280204-A1 USE OF EXTRACTS OF CAPRARIA BIFLORA IN THE PREVENTION AND/OR TREATMENT OF SENILE CATARACTS BURROWS ENTERPRISES, LLC 2009-11-12 US disclosed
WO-2009137303-A2 USE OF EXTRACTS OF CAPRARIA BIFLORA IN THE PREVENTION AND/OR TREATMENT OF SENILE CATARACTS BURROWS ENTERPRISES, LLC (US) 2009-11-12 WO disclosed