Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91161 | 0.93 | — | — | |
| Bromide SCHEMBL30954806 | 0.90 | — | — | |
| Water SCHEMBL28101650 | 0.90 | — | — | |
| SCHEMBL2950896 | 0.90 | — | — | |
| SCHEMBL28782240 | 0.90 | — | — | |
| Ammonia Solution, Strong SCHEMBL3574809 | 0.90 | — | — | |
| Methylamine SCHEMBL27553311 | 0.88 | TAAR1 (0.54) | HPGDRAB9ASMN1; SMN2MEN1KMT2A | |
| Methylamine SCHEMBL11471748 | 0.88 | — | — | |
| Trimethylammonium SCHEMBL20817131 | 0.86 | MEN1 (0.47) | HPGDRAB9ASMN1; SMN2MEN1KMT2A | |
| Dimethylamine SCHEMBL4430498 | 0.86 | MEN1 (0.52) | HPGDRAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888786-A1 | HYDROPROCESSING BULK CATALYST AND USES THEREOF | Chevron U.S.A. Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| EP-2504099-B1 | HYDROPROCESSING BULK CATALYST, IT'S USE AND METHODS OF MAKING THEREOF | CHEVRON USA INC (US) | 2021-08-11 | — | — | EP | disclosed |
| US-8431511-B2 | Hydroprocessing bulk catalyst and methods of making thereof | CHEVRON U.S.A. INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-8420565-B2 | Hydroprocessing bulk catalyst and methods of making thereof | CHEVRON U.S.A. INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-8389433-B2 | Hydroprocessing bulk catalyst and methods of making thereof | CHEVRON U.S.A. (US) | 2013-03-05 | — | — | US | disclosed |
| US-8372776-B2 | Hydroprocessing bulk catalyst and methods of making thereof | CHEVRON U.S.A. INC. (US) | 2013-02-12 | — | — | US | disclosed |
| EP-2504099-A2 | HYDROPROCESSING BULK CATALYST AND METHODS OF MAKING THEREOF | Chevron U.S.A. Inc. (US) | 2012-10-03 | — | — | EP | disclosed |
| WO-2011066150-A2 | HYDROPROCESSING BULK CATALYST AND METHODS OF MAKING THEREOF | CHEVRON U.S.A. INC. (US) | 2011-06-03 | — | — | WO | disclosed |
| US-20110124496-A1 | Hydroprocessing Bulk Catalyst and Methods of Making Thereof | CHEVRON U.S.A. INC. | 2011-05-26 | — | — | US | disclosed |
| US-20110124498-A1 | Hydroprocessing Bulk Catalyst and Methods of Making Thereof | CHEVRON U.S.A. INC. | 2011-05-26 | — | — | US | disclosed |
| US-7678730-B2 | Hydroprocessing bulk catalyst and uses thereof | CHEVRON USA INC. (US) | 2010-03-16 | — | — | US | disclosed |
| WO-2009058861-A2 | HYDROPROCESSING BULK CATALYST AND USES THEREOF | CHEVRON U.S.A. INC. (US) | 2009-05-07 | — | — | WO | disclosed |
| US-20090057201-A1 | HYDROPROCESSING BULK CATALYST AND USES THEREOF | CHEVRON U.S.A. INC | 2009-03-05 | — | — | US | disclosed |
| US-20090054226-A1 | Hydroprocessing Bulk Catalyst and Uses Thereof | CHEVRON U.S.A. INC | 2009-02-26 | — | — | US | disclosed |
| US-20090054225-A1 | Hydroprocessing Bulk Catalyst and Uses Thereof | CHEVRON U.S.A. INC | 2009-02-26 | — | — | US | disclosed |
| US-5821397-A | SUPPORTED PALLADIUM | INSTITUT FRANCAIS DU PETROLE (FR) | 1998-10-13 | — | — | US | disclosed |
| US-5569806-A | GROUP EIGHT METAL ON SUPPORT | INSTITUT FRANCAIS DU PETROLE (FR) | 1996-10-29 | — | — | US | disclosed |
| US-5502269-A | Process for the isomerization of external olefins to internal olefins concomitantly with diolefin hydrogenation | INSTITUT FRANCAIS DU PETROLE (FR) | 1996-03-26 | — | — | US | disclosed |
| US-5417844-A | Sulfur compounds | INSTITUT FRANCAIS DU PETROLE (FR) | 1995-05-23 | — | — | US | disclosed |
| US-5169819-A | Impregnation of supported catalyst with aqueous ammonium sulfide solution which also contains sulfur-compound adjuvants then controlled heating | EUROPEENNE DE RETRAITEMENT DE CATALYSEURS (FR) | 1992-12-08 | — | — | US | disclosed |