⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91161 | 0.97 | — | — | |
| Bromide SCHEMBL30954806 | 0.95 | — | — | |
| SCHEMBL2950896 | 0.95 | — | — | |
| Water SCHEMBL28101650 | 0.95 | — | — | |
| SCHEMBL28782240 | 0.95 | — | — | |
| Methylamine SCHEMBL11471748 | 0.92 | — | — | |
| Methylamine SCHEMBL27553311 | 0.92 | TAAR1 (0.54) | — | |
| Dimethylamine SCHEMBL4430498 | 0.90 | MEN1 (0.52) | — | |
| Trimethylammonium SCHEMBL20817131 | 0.90 | MEN1 (0.47) | — | |
| Alcohol SCHEMBL1765824 | 0.90 | HPGD (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447731-A | Preparation method of 2-formylamine-5-(2-sulfhydryl-1, 3-thiazole-4-base)-thiophene | CHEER FINE PHARMACEUTICAL ANHUI CO LTD | 2015-03-25 | — | — | CN | claimed |
| CN-118344344-A | Pyrimidine compound containing 5-carboxylic acid isopropyl ester and application thereof | 江西科技师范大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-115433160-B | Analgesic active compounds and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-06-30 | — | — | CN | disclosed |
| CN-114539137-B | Chiral alpha-heteroaryl amine and preparation method thereof | 河北工业大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-115433160-A | Analgesic active compound and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-12-06 | — | — | CN | disclosed |
| CN-112047935-A | Autophagy targeting protein degradation technology and application thereof | 上海强睿生物科技有限公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-104447731-A | Preparation method of 2-formylamine-5-(2-sulfhydryl-1, 3-thiazole-4-base)-thiophene | CHEER FINE PHARMACEUTICAL ANHUI CO LTD | 2015-03-25 | — | — | CN | disclosed |
| CN-104447731-A | Preparation method of 2-formylamine-5-(2-sulfhydryl-1, 3-thiazole-4-base)-thiophene | CHEER FINE PHARMACEUTICAL ANHUI CO LTD | 2015-03-25 | — | — | CN | disclosed |
| US-7696351-B2 | Process for the preparation of S-(+)-clopidogrel by optical resolution | SK CHEMICALS CO., LTD. (KR) | 2010-04-13 | — | — | US | disclosed |
| US-20090275755-A1 | Process for the Preparation of S-(+)-Clopidogrel by Optical Resolution | SK CHEMICALS CO., LTD. (KR) | 2009-11-05 | — | — | US | disclosed |
| EP-1966219-A1 | PROCESS FOR THE PREPARATION OF S-(+)-CLOPIDOGREL BY OPTICAL RESOLUTION | SK CHEMICALS CO., LTD. (KR) | 2008-09-10 | — | — | EP | disclosed |
| WO-2008018779-A1 | PROCESS FOR HIGH YIELD PRODUCTION OF CLOPIDOGREL BY RACEMIZATION OF RESIDUAL LIQUID | SK CHEMICALS CO., LTD. (KR) | 2008-02-14 | — | — | WO | disclosed |
| WO-2007074995-A1 | PROCESS FOR THE PREPARATION OF S-(+)-CLOPIDOGREL BY OPTICAL RESOLUTION | SK CHEMICALS CO., LTD. (KR) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007073095-A1 | PROCESS FOR THE PREPARATION OF (S)-(+)-CLOPIDOGREL ON A SOLID-PHASE | SK CHEMICALS CO., LTD. (KR) | 2007-06-28 | — | — | WO | disclosed |
| CN-1805951-A | Substituted piperidine carbamates for use as inhibitors of hormone sensitive lipase | NOVO NORDISK AS (DK) | 2006-07-19 | — | — | CN | disclosed |
| EP-0000453-B1 | PROCESS FOR THE PREPARATION OF THIENOPYRIDINE DERIVATIVES. | OMNIUM FINANCIER AQUITAINE POUR L'HYGIENE ET LA SANTE - SANOFI (FR) | 1980-07-23 | — | — | EP | disclosed |
| US-4174448-A | ALKYLATION, CYCLIZATION | PARCOR (FR) | 1979-11-13 | — | — | US | disclosed |