⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91161 | 0.97 | — | — | |
| Bromide SCHEMBL30954806 | 0.95 | — | — | |
| Water SCHEMBL28101650 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL3574809 | 0.95 | — | — | |
| SCHEMBL28782240 | 0.95 | — | — | |
| Methylamine SCHEMBL27553311 | 0.92 | TAAR1 (0.54) | — | |
| Methylamine SCHEMBL11471748 | 0.92 | — | — | |
| Dimethylamine SCHEMBL4430498 | 0.90 | MEN1 (0.52) | — | |
| Alcohol SCHEMBL1765824 | 0.90 | HPGD (0.47) | — | |
| Trimethylammonium SCHEMBL20817131 | 0.90 | MEN1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3741758-A1 | BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2020-11-25 | — | — | EP | disclosed |
| US-20200354371-A1 | BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2020-11-12 | — | — | US | disclosed |
| CN-103983681-A | Electrochemical sensor for detecting heavy metals and preparation method and application thereof | UNIV HUNAN | 2014-08-13 | — | — | CN | disclosed |
| CN-103748142-A | Reversibly crosslinked micelle systems | UNIV CALIFORNIA | 2014-04-23 | — | — | CN | disclosed |
| US-7795228-B2 | Spiroheterocyclic glycosides and methods of use | THERACOS, INC. (US) | 2010-09-14 | — | — | US | disclosed |
| US-20100184764-A1 | CYCLOALKYL LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | ELI LILLY AND COMPANY (US) | 2010-07-22 | — | — | US | disclosed |
| US-7754403-B2 | asymmetric bishydroxy compound having an excellent charge transporting performance as well as excellent solubility in the solvent and compatibility with the resin where no partial crystals are created at the time of film formation, and electrical properties and durability are both excellent | SHARP KABUSHIKI KAISHA (JP) | 2010-07-13 | — | — | US | disclosed |
| US-7713979-B2 | Cycloalkyl lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 | ELI LILLY AND COMPANY (US) | 2010-05-11 | — | — | US | disclosed |
| EP-1530470-B9 | SELECTIVE ESTROGEN RECEPTOR MODULATORS CONTAINING A PHENYLSULFONYL GROUP | LILLY CO ELI (US) | 2010-04-07 | — | — | EP | disclosed |
| US-7585977-B2 | Selective estrogen receptor modulators containing a phenylsulfonyl group | ELI LILLY AND COMPANY (US) | 2009-09-08 | — | — | US | disclosed |
| US-20070207395-A1 | Electrophotoconductor and image forming apparatus | SHARP KABUSHIKI KAISHA (JP) | 2007-09-06 | — | — | US | disclosed |
| EP-1807072-A1 | CYCLOALKYL LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | ELI LILLY AND COMPANY (US) | 2007-07-18 | — | — | EP | disclosed |
| EP-1782810-A2 | Selective estrogen receptor modulators containing a phenylsulfonyl group | Eli Lilly & Company (US) | 2007-05-09 | — | — | EP | disclosed |
| US-20060183736-A1 | Selective estrogen receptor modulators containing a phenylsulfonyl group | ELILILLY AND COMPANY | 2006-08-17 | — | — | US | disclosed |
| WO-2006049952-A1 | CYCLOALKYL LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | ELI LILLY AND COMPANY (US) | 2006-05-11 | — | — | WO | disclosed |
| EP-1530470-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS CONTAINING A PHENYLSULFONYL GROUP | ELI LILLY AND COMPANY (US) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004009086-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS CONTAINING A PHENYLSULFONYL GROUP | ELI LILLY AND COMPANY (US) | 2004-01-29 | — | — | WO | disclosed |
| EP-0823437-B1 | 8-Substituted B-nor-6-thiaequilenin compounds having activity as selective estrogen receptor modulators | LILLY CO ELI (US) | 2003-04-09 | — | — | EP | disclosed |
| US-6218425-B1 | USEFUL IN THE TREATMENT OF ESTROGEN-RELATED DISORDERS SUCH AS OSTEOPOROSIS, HYPERLIPIDEMIA, ESTROGEN-RELATED BREAST CANCER, UTERINE FIBROSIS, ENDOMETRIOSIS, AND RESTENOSIS | ELI LILLY AND COMPANY | 2001-04-17 | — | — | US | disclosed |
| EP-0823437-A2 | 8-Substituted B-nor-6-thiaequilenin compounds having activity as selective estrogen receptor modulators | ELI LILLY AND COMPANY (US) | 1998-02-11 | — | — | EP | disclosed |