Sugi Predict

Sugi Predict / Compounds / SCHEMBL17658353

SCHEMBL17658353

SCHEMBL17658353

C[Si](C)(C)c1ccc(N(c2ccccc2)c2ccc3c(c2)oc2c4ccc(N(c5ccccc5)c5ccc6oc7ccccc7c6c5)cc4c4ccccc4c32)cc1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.32
▸ NPC1 O15118 2/20 0.32
▸ KDM4E B2RXH2 3/20 0.32
▸ MEN1 O00255 3/20 0.32
▸ HPGD P15428 3/20 0.32
▸ KMT2A Q03164 3/20 0.32
▸ AHR P35869 2/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ CYP3A4 P08684 1/20 0.32
▸ ALPI P09923 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ PKM P14618 1/20 0.32
▸ CASP3 P42574 1/20 0.32
▸ RECQL P46063 1/20 0.32
▸ BLM P54132 1/20 0.32
▸ CASP7 P55210 1/20 0.32
▸ CASP6 P55212 1/20 0.32
▸ MCL1 Q07820 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17658367 0.98 AHR (0.33) MAPTKDM4EMEN1HPGDKMT2A
SCHEMBL17658531 0.98 MAPT (0.33) MAPTNPC1KDM4EMEN1HPGD
SCHEMBL17658428 0.95 PTPRF (0.32) —
SCHEMBL17658366 0.93 MEN1 (0.33) MAPTKDM4EMEN1HPGDKMT2A
SCHEMBL17658313 0.93 MEN1 (0.33) MAPTKDM4EMEN1HPGDKMT2A
SCHEMBL17658380 0.93 MEN1 (0.33) MAPTKDM4EMEN1HPGDKMT2A
SCHEMBL17658345 0.92 MAPT (0.37) MAPTNPC1KDM4EMEN1HPGD
SCHEMBL17658361 0.92 KDM4E (0.31) MAPTKDM4EMEN1HPGDKMT2A
SCHEMBL17658387 0.92 KDM4E (0.31) MAPTKDM4EMEN1HPGDKMT2A
SCHEMBL17658355 0.91 CDC14B (0.30) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9923147-B2 Organic light emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-20 — — US disclosed
US-9923147-B2 Organic light emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-20 — — US disclosed
US-9856243-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-01-02 — — US disclosed
US-20160329501-A1 ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-11-10 — — US disclosed
US-20160329501-A1 ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-11-10 — — US disclosed
EP-3006436-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2016-04-13 — — EP disclosed
US-20160099423-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-07 — — US disclosed
US-20160099423-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160099423-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, MCM4 MAPT 1667/4885NPC1 857/4885KDM4E 3126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.