Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 7/20 | 0.37 |
| ▸ | FLT1 | P17948 | 4/20 | 0.37 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.35 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | KIT | P10721 | 2/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | CDK11B | P21127 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | CDKL2 | Q92772 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17658740 | 0.83 | GSK3B (0.47) | GSK3BKDRFLT1ADCY1ADCY8 | |
| SCHEMBL627855 | 0.77 | GSK3B (0.51) | GSK3BKDRFLT1ADCY1ADCY8 | |
| SCHEMBL12336259 | 0.76 | GSK3B (0.45) | GSK3BKDRFLT1ADCY1PDGFRB | |
| SCHEMBL12336275 | 0.72 | KDR (0.51) | GSK3BKDRFLT1ADCY1ADCY8 | |
| SCHEMBL17662111 | 0.71 | GSK3B (0.43) | GSK3BKDRFLT1ADCY1PDGFRB | |
| SCHEMBL14949499 | 0.70 | PDGFRB (0.44) | GSK3BKDRFLT1ADCY1PDGFRB | |
| SCHEMBL12336297 | 0.69 | KDR (0.59) | GSK3BKDRFLT1PDGFRBKIT | |
| SCHEMBL626404 | 0.68 | PDGFRB (0.65) | GSK3BKDRFLT1ADCY1ADCY8 | |
| SCHEMBL17661758 | 0.68 | LMNA (0.47) | GSK3BKDRFLT1PDGFRBKIT | |
| SCHEMBL12336273 | 0.68 | PDGFRB (0.57) | GSK3BKDRFLT1ADCY1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160096824-A1 | Heterocyclic Compounds Useful for Kinase Inhibition | AMITECH THERAPEUTIC SOLUTIONS, INC. | 2016-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096824-A1 | Heterocyclic Compounds Useful for Kinase Inhibition | MAP4K2, MAP3K20, MAP3K19 | GSK3B 581/4885KDR 533/4885FLT1 977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.