Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 5/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29484746 | 0.83 | MGAM (0.68) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| SCHEMBL31080661 | 0.83 | MGAM (0.57) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| SCHEMBL28879874 | 0.83 | LMNA (0.65) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| SCHEMBL611196 | 0.83 | MGAM (0.57) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| SCHEMBL403888 | 0.83 | MGAM (0.68) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| SCHEMBL29484748 | 0.83 | MGAM (0.68) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3199562 | 0.81 | MGAM (0.66) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| SCHEMBL19046659 | 0.81 | MGAM (0.55) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| SCHEMBL8307051 | 0.79 | MGAM (0.53) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| SCHEMBL1343443 | 0.77 | CNR2 (0.78) | MGAMLMNACNR2HDAC8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464349-A2 | USE OF PPAR DELTA LIGANDS FOR THE TREATMENT OR PREVENTION OF INFLAMMATION OR ENERGY METABOLISM/PRODUCTION RELATED DISEASES | Cerenis Therapeutics S.A. (FR) | 2012-06-20 | — | — | EP | disclosed |
| WO-2011020001-A9 | USE OF PPAR DELTA LIGANDS FOR THE TREATMENT OR PREVENTION OF INFLAMMATION OR ENERGY METABOLISM/PRODUCTION RELATED DISEASES | CERENIS THERAPEUTICS S.A. (FR) | 2011-05-26 | — | — | WO | disclosed |
| WO-2011020001-A2 | USE OF PPAR DELTA LIGANDS FOR THE TREATMENT OR PREVENTION OF INFLAMMATION OR ENERGY METABOLISM/PRODUCTION RELATED DISEASES | CERENIS THERAPEUTICS S.A. (FR) | 2011-02-17 | — | — | WO | disclosed |
| WO-2008154023-A1 | NOVEL USES OF PPAR DELTA AGONISTS | CERENIS THERAPEUTICS S.A. (FR) | 2008-12-18 | — | — | WO | disclosed |