Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 5/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31080661 | 1.00 | MGAM (0.57) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| Quinoline SCHEMBL28307189 | 0.89 | ALDH1A1 (0.57) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| SCHEMBL28443611 | 0.83 | MGAM (0.61) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| SCHEMBL1765896 | 0.83 | MGAM (0.61) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| SCHEMBL28198335 | 0.81 | MGAM (0.59) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| SCHEMBL12256867 | 0.81 | MGAM (0.64) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| SCHEMBL29484748 | 0.79 | MGAM (0.68) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| SCHEMBL28879874 | 0.79 | LMNA (0.65) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| SCHEMBL29484746 | 0.79 | MGAM (0.68) | MGAMLMNACNR2HDAC8ALDH1A1 | |
| SCHEMBL403888 | 0.79 | MGAM (0.68) | MGAMLMNACNR2HDAC8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023208173-A1 | SUBSTITUTED 6- (PYRIMIDIN-4-YL) QUINOLINE COMPOUNDS AS CYCLIN DEPENDENT KINASE INHIBITORS | BEIGENE , LTD. (KY) | 2023-11-02 | — | — | WO | disclosed |
| CN-110036047-B | Methacrylic copolymer and molded article | 株式会社可乐丽 | 2021-01-05 | — | — | CN | disclosed |
| US-10875996-B2 | Methacrylic copolymer and molded article | KURARAY CO., LTD. (JP) | 2020-12-29 | — | — | US | disclosed |
| US-20200317902-A1 | METHACRYLIC COPOLYMER AND MOLDED ARTICLE | KURARAY CO., LTD. (JP) | 2020-10-08 | — | — | US | disclosed |
| WO-2020147848-A1 | TRICYCLIC SUBSTITUTED OXASPIRO DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 上海海雁医药科技有限公司 | 2020-07-23 | — | — | WO | disclosed |
| EP-3239183-B1 | MODIFIED CONJUGATED DIENE POLYMER, AND POLYMER COMPOSITION CONTAINING SAID POLYMER | SUMITOMO CHEMICAL CO (JP) | 2020-03-11 | — | — | EP | disclosed |
| EP-3564275-A1 | METHACRYLIC COPOLYMER AND MOLDED ARTICLE | Kuraray Co., Ltd. (JP) | 2019-11-06 | — | — | EP | disclosed |
| EP-2957579-B1 | COPOLYMER AND MOLDED BODY | KURARAY CO (JP) | 2019-10-02 | — | — | EP | disclosed |
| US-10407524-B2 | Copolymer and molded article | KURARAY CO., LTD. (JP) | 2019-09-10 | — | — | US | disclosed |
| US-10287380-B2 | Copolymer, and molded article | KURARAY CO., LTD. (JP) | 2019-05-14 | — | — | US | disclosed |
| US-5230711-A | DYEING OF CELLULOSE WITH SOLUBLE SULPHUR DYES WITHOUT REDUCING AGENT | CASSELLA AG (DE) | 1993-07-27 | — | — | US | disclosed |
| EP-0509277-A1 | Process for dyeing cellulose with sulfur dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-21 | — | — | EP | disclosed |
| EP-0509397-A1 | Process for dyeing modified with N-containing, basic polymers cellulosic fibrous material with anionic dyestuffs and the modified cellulosic fibrous material by itself | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-21 | — | — | EP | disclosed |
| EP-0454173-A2 | Shape-memorizing block copolymer composition | NIPPON ZEON CO., LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |
| EP-0366486-A2 | A shape-memorizable block copolymer, the method of using it and shape memory products | NIPPON ZEON CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |
| US-4686243-A | ADDITION POLYMERS OF HETEROCYCLES, DIALLYLDIALKYLAMMONIUM HALIDES, EPOXIDES OR AZIRIDINES | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-08-11 | — | — | US | disclosed |
| EP-0131179-B1 | COPOLYMER, PROCESS FOR ITS PREPARATION AND ITS USE AS A SORBENT | CASSELLA Aktiengesellschaft (DE) | 1987-06-16 | — | — | EP | disclosed |
| EP-0220593-A1 | Copolymer, process for its preparation and its use in the bonding of enzymes | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-05-06 | — | — | EP | disclosed |
| US-4552905-A | VINYL-SUBSTITUTED PYRIDINE, QUINOLINE, ISO-QUINOLINE, OR PYRAZINE;N-VINYLAMIDE, CROSSLINKER | CASSELLA AKTIENGESELLSCHAFT (DE) | 1985-11-12 | — | — | US | disclosed |
| EP-0131179-A1 | Copolymer, process for its preparation and its use as a sorbent | CASSELLA Aktiengesellschaft (DE) | 1985-01-16 | — | — | EP | disclosed |