Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.54 |
| ▸ | PPARD | Q03181 | 16/20 | 0.54 |
| ▸ | PPARG | P37231 | 10/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755232 | 0.92 | PPARA (0.46) | PPARAPPARDPPARGNPC1POLB | |
| SCHEMBL1765901 | 0.88 | PPARA (0.50) | PPARAPPARDPPARGNPC1POLB | |
| SCHEMBL4754079 | 0.87 | PPARD (0.62) | PPARAPPARDPPARGNPC1POLB | |
| SCHEMBL2463893 | 0.85 | PPARD (0.60) | PPARAPPARDPPARGNPC1POLB | |
| SCHEMBL2463809 | 0.85 | PPARA (0.56) | PPARAPPARDPPARGNPC1POLB | |
| SCHEMBL1765951 | 0.84 | PPARD (0.58) | PPARAPPARDPPARGNPC1POLB | |
| SCHEMBL12732421 | 0.81 | PPARA (0.48) | PPARAPPARDPPARGNPC1POLB | |
| SCHEMBL1765978 | 0.80 | PPARA (0.61) | PPARAPPARDPPARGNPC1POLB | |
| SCHEMBL12732408 | 0.79 | PPARA (0.51) | PPARAPPARDPPARGNPC1POLB | |
| SCHEMBL2466184 | 0.79 | PPARD (0.52) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464349-A2 | USE OF PPAR DELTA LIGANDS FOR THE TREATMENT OR PREVENTION OF INFLAMMATION OR ENERGY METABOLISM/PRODUCTION RELATED DISEASES | Cerenis Therapeutics S.A. (FR) | 2012-06-20 | — | — | EP | disclosed |
| WO-2011020001-A9 | USE OF PPAR DELTA LIGANDS FOR THE TREATMENT OR PREVENTION OF INFLAMMATION OR ENERGY METABOLISM/PRODUCTION RELATED DISEASES | CERENIS THERAPEUTICS S.A. (FR) | 2011-05-26 | — | — | WO | disclosed |
| WO-2011020001-A2 | USE OF PPAR DELTA LIGANDS FOR THE TREATMENT OR PREVENTION OF INFLAMMATION OR ENERGY METABOLISM/PRODUCTION RELATED DISEASES | CERENIS THERAPEUTICS S.A. (FR) | 2011-02-17 | — | — | WO | disclosed |
| WO-2008154023-A1 | NOVEL USES OF PPAR DELTA AGONISTS | CERENIS THERAPEUTICS S.A. (FR) | 2008-12-18 | — | — | WO | disclosed |