Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 4/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1765952 | 0.92 | PPARA (0.54) | PPARAPPARGPPARDTSHRMAPT | |
| SCHEMBL2468027 | 0.86 | PPARA (0.50) | PPARAPPARGPPARDTSHRMAPT | |
| SCHEMBL2466177 | 0.86 | PPARA (0.47) | PPARAPPARGPPARDTSHRMAPT | |
| SCHEMBL1765901 | 0.86 | PPARA (0.50) | PPARAPPARGPPARDTSHRMAPT | |
| SCHEMBL2466219 | 0.85 | PPARA (0.49) | PPARAPPARGPPARDTSHRMAPT | |
| SCHEMBL4754079 | 0.83 | PPARD (0.62) | PPARAPPARGPPARDTSHRMAPT | |
| SCHEMBL2463966 | 0.82 | PPARA (0.51) | PPARAPPARGPPARDTSHRMAPT | |
| SCHEMBL2460886 | 0.80 | PPARA (0.43) | PPARAPPARGPPARDTSHRMAPT | |
| SCHEMBL12732421 | 0.79 | PPARA (0.48) | PPARAPPARGPPARDTSHRMAPT | |
| SCHEMBL12732408 | 0.78 | PPARA (0.51) | PPARAPPARGPPARDTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154023-A1 | NOVEL USES OF PPAR DELTA AGONISTS | CERENIS THERAPEUTICS S.A. (FR) | 2008-12-18 | — | — | WO | disclosed |