Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 12/20 | 0.62 |
| ▸ | PPARG | P37231 | 5/20 | 0.62 |
| ▸ | PPARA | Q07869 | 5/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1765901 | 0.89 | PPARA (0.50) | PPARDPPARGPPARATSHRNPC1 | |
| SCHEMBL1765952 | 0.87 | PPARA (0.54) | PPARDPPARGPPARATSHRNPC1 | |
| SCHEMBL1765854 | 0.87 | PPARD (0.62) | PPARDPPARGPPARATDP1TSHR | |
| SCHEMBL2463908 | 0.87 | PPARD (0.62) | PPARDPPARGPPARATDP1TSHR | |
| SCHEMBL2460872 | 0.85 | PPARD (0.64) | PPARDPPARGPPARATDP1TSHR | |
| SCHEMBL1765936 | 0.85 | PPARD (0.68) | PPARDPPARGPPARATDP1TSHR | |
| SCHEMBL1765900 | 0.84 | PPARD (0.66) | PPARDPPARGPPARATDP1TSHR | |
| SCHEMBL4755232 | 0.83 | PPARA (0.46) | PPARDPPARGPPARATSHRNPC1 | |
| SCHEMBL12732407 | 0.82 | PPARG (0.54) | PPARDPPARGPPARATDP1TSHR | |
| SCHEMBL12732423 | 0.80 | PPARA (0.55) | PPARDPPARGPPARATDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154023-A1 | NOVEL USES OF PPAR DELTA AGONISTS | CERENIS THERAPEUTICS S.A. (FR) | 2008-12-18 | — | — | WO | disclosed |