SCHEMBL1766

SCHEMBL1766

Clc1ccc(CBr)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4358863 0.97 IDO1 (0.50)
SCHEMBL11026325 0.97 IDO1 (0.50)
Benzene SCHEMBL28841146 0.94 TSHR (0.60)
SCHEMBL6756387 0.92 MAOB (0.52)
SCHEMBL11527604 0.85 AHR (0.52)
SCHEMBL11527600 0.85 AHR (0.52)
SCHEMBL6824043 0.85 MAOB (0.52)
SCHEMBL18166891 0.83 IDO1 (0.39)
SCHEMBL131361 0.83 ALDH1A1 (0.67)
SCHEMBL1744667 0.82 SRD5A2 (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4664 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115959962-B Visible light-promoted halogenated alkane hydrodehalogenation method 中国科学院兰州化学物理研究所 2025-05-23 CN claimed
CN-115850002-B Method for hydrodehalogenating halogenated alkane 中国科学院兰州化学物理研究所 2025-05-23 CN claimed
US-12304917-B1 Pleuromutilin derivative containing a thiazolo[5,4-c]pyridine side chain, and a preparation method and application thereof SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2025-05-20 US claimed
CN-119912847-A Composite coating and application thereof 万华化学集团股份有限公司 2025-05-02 CN claimed
US-12275734-B1 Pleuromutilin onium salt derivative containing a 3H-imidazo[4,5-c]pyridine side chain, and a preparation method and application thereof SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2025-04-15 US claimed
CN-119684613-A Nanocomposite capable of adjusting synaptic plasticity and preparation method thereof 南方医科大学口腔医院 2025-03-25 CN claimed
CN-119569808-A Method for modifying C-21 position structure of fusidic acid 浙江工业大学 2025-03-07 CN claimed
CN-119263950-A Synthesis method of 1, 2-bis (4-vinyl phenyl) ethane 上海康鹏科技股份有限公司 2025-01-07 CN claimed
CN-119101052-A Matrine-triazole derivative and synthesis method thereof 吉林医药学院 2024-12-10 CN claimed
CN-118221691-B Methylenedioxybenzo [ b ] [1,4] diazepine [5,6-e ] triazinone derivative and pharmaceutically acceptable salt, preparation method and application thereof 常熟理工学院 2024-10-15 CN claimed
US-6028181-A 6-0-Substituted antibacterial erythromycin ketolides and methods of making ABBOTT LABORATORIES (US) 2000-02-22 US claimed
EP-0929563-A1 6-O-SUBSTITUTED KETOLIDES HAVING ANTIBACTERIAL ACTIVITY Abbott Laboratories (US) 1999-07-21 EP claimed
EP-0918783-A1 6-O-SUBSTITUTED ERYTHROMYCINS AND METHOD FOR MAKING THEM ABBOTT LABORATORIES (US) 1999-06-02 EP claimed
US-5837868-A REACTION OF DIHYDROXY OLEFINS IN A MULTISTAGE PROCESS ARYL METHYLAMINE TO FORM PYRROLIDINE INTERMEDIATE ABBOTT LABORATORIES (US) 1998-11-17 US claimed
WO-1998022437-A1 PROCESS FOR PREPARATION OF CHIRAL 3-AMINOPYRROLIDINE AND ANALOGOUS BICYCLIC COMPOUNDS ABBOTT LABORATORIES (US) 1998-05-28 WO claimed
WO-1998009978-A1 6-O-SUBSTITUTED KETOLIDES HAVING ANTIBACTERIAL ACTIVITY ABBOTT LABORATORIES (US) 1998-03-12 WO claimed
US-5703244-A CYCLIZATION OF DIHYDROXY OLEFINS WITH TARTRATE ESTER IN PRESENCE OF TITANIUM ISOPROPOXIDE AND TERT-BUTYL HYDROPEROXIDE ABBOTT LABORATORIES (US) 1997-12-30 US claimed
WO-1997042206-A1 6-O-SUBSTITUTED ERYTHROMYCIN COMPOUNDS AND METHOD FOR MAKING SAME ABBOTT LABORATORIES (US) 1997-11-13 WO claimed
WO-1997042204-A1 6-O-SUBSTITUTED ERYTHROMYCINS AND METHOD FOR MAKING THEM ABBOTT LABORATORIES (US) 1997-11-13 WO claimed
US-4554356-A Method for production of imidazolyl vinyl ethers SIEGFRIED AKTIENGESELLSCHAFT (CH) 1985-11-19 US claimed