Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885219 | 0.88 | ST14 (0.48) | LTA4HST14 | |
| SCHEMBL1766 | 0.85 | — | — | |
| SCHEMBL1563522 | 0.85 | CARM1 (0.46) | MAOBMAOAS1PR5PPARGPPARA | |
| SCHEMBL4358863 | 0.83 | IDO1 (0.50) | MAOBIDO1AGXT | |
| SCHEMBL11026325 | 0.83 | IDO1 (0.50) | MAOBIDO1AGXT | |
| SCHEMBL9293968 | 0.83 | MAOB (0.48) | MAOBMAOAS1PR5PPARGPPARA | |
| SCHEMBL30302090 | 0.82 | MAOA (0.44) | MAOBMAOAS1PR5PPARGPPARA | |
| SCHEMBL20566300 | 0.82 | MAOA (0.44) | MAOBMAOAS1PR5PPARGPPARA | |
| SCHEMBL10870044 | 0.81 | MAOB (0.56) | MAOBMAOAS1PR5PPARGPPARA | |
| SCHEMBL9428779 | 0.81 | LPAR1 (0.44) | MAOBST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014095249-A1 | FUNGICIDAL IMIDAZOLYL AND TRIAZOLYL COMPOUNDS | BASF SE (DE) | 2014-06-26 | — | — | WO | disclosed |
| CN-1523958-A | Pesticide compositions comprising malononitrile compounds | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-08-25 | — | — | CN | disclosed |
| US-20040142821-A1 | Pesticide composition comprising malononitrile compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-07-22 | — | — | US | disclosed |
| EP-1385377-A1 | PESTICIDE COMPOSITION COMPRISING MALONONITRILE COMPOUNDS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002089579-A1 | PESTICIDE COMPOSITION COMPRISING MALONONITRILE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142821-A1 | Pesticide composition comprising malononitrile compounds | CBR1, CBR3, ME1 | MAOB 4093/4885MAOA 4042/4885S1PR5 2132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.