Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865381 | 0.88 | HPGD (0.57) | MLYCDHPGDNPSR1EPHX2NR1H4 | |
| SCHEMBL13753069 | 0.83 | EPHX2 (0.63) | EPHX2NR1H4TRPV1PPARGPPARA | |
| SCHEMBL13876984 | 0.82 | TRPV1 (0.55) | EPHX2NR1H4TRPV1PPARGPPARA | |
| SCHEMBL17865783 | 0.82 | MLYCD (0.73) | MLYCDHPGDNPSR1EPHX2GAA | |
| SCHEMBL24225548 | 0.81 | HPGD (0.71) | MLYCDHPGDNPSR1GAAKMT2A | |
| SCHEMBL13702138 | 0.81 | MLYCD (0.65) | MLYCDNPSR1EPHX2NR1H4TRPV1 | |
| SCHEMBL19472407 | 0.80 | EPHX2 (0.60) | EPHX2NR1H4TRPV1PPARGPPARA | |
| SCHEMBL13753142 | 0.80 | HDAC3 (0.66) | EPHX2NR1H4TRPV1PPARGPPARA | |
| SCHEMBL12966949 | 0.80 | MCHR1 (0.56) | EPHX2NR1H4TRPV1PPARGPPARA | |
| SCHEMBL12020316 | 0.80 | EPHX2 (0.59) | EPHX2NR1H4TRPV1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10253023-B2 | Heteroaryl compounds as BTK inhibitors and uses thereof | MERCK PATENT GMBH (DE) | 2019-04-09 | — | — | US | disclosed |
| US-20160096834-A1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2016-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10253023-B2 | Heteroaryl compounds as BTK inhibitors and uses thereof | BTK, SYK, LYN | MLYCD 3603/4885HPGD 3809/4885NPSR1 4440/4885 |
| US-20160096834-A1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | BTK, SYK, LYN | MLYCD 3603/4885HPGD 3809/4885NPSR1 4440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.