SCHEMBL17865783

SCHEMBL17865783

CC(C)CNC(=O)c1ccc(C(=O)NCC(C)C)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 1/20 0.73
KMT2A Q03164 3/20 0.71
GAA P10253 1/20 0.71
HSD17B10 Q99714 1/20 0.71
HPGD P15428 2/20 0.71
NPSR1 Q6W5P4 1/20 0.71
KDM4E B2RXH2 3/20 0.62
ALDH1A1 P00352 4/20 0.57
ALOX12 P18054 3/20 0.57
RAB9A P51151 3/20 0.57
NPC1 O15118 2/20 0.57
LMNA P02545 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
KCNH2 Q12809 1/20 0.57
NAMPT P43490 1/20 0.55
ACACB O00763 1/20 0.55
HDAC4 P56524 1/20 0.54
MEN1 O00255 2/20 0.53
EPHX2 P34913 1/20 0.52
HTT P42858 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL162726 0.92 MLYCD (0.65) MLYCDKMT2AGAAHSD17B10HPGD
SCHEMBL178516 0.92 MLYCD (0.65) MLYCDKMT2AGAAHSD17B10HPGD
SCHEMBL104285 0.90 HPGD (0.63) MLYCDKMT2AGAAHSD17B10HPGD
SCHEMBL5940582 0.90 MLYCD (0.63) MLYCDKMT2AGAAHSD17B10HPGD
SCHEMBL6755639 0.90 ALDH1A1 (0.71) MLYCDKMT2AGAAHSD17B10HPGD
SCHEMBL23665801 0.90 MLYCD (0.63) MLYCDKMT2AGAAHSD17B10HPGD
SCHEMBL889069 0.90 MLYCD (0.63) MLYCDKMT2AGAAHSD17B10HPGD
SCHEMBL3056083 0.90 MLYCD (0.63) MLYCDKMT2AGAAHSD17B10HPGD
SCHEMBL255251 0.90 GAA (0.76) MLYCDKMT2AGAAHSD17B10HPGD
SCHEMBL10203248 0.89 MLYCD (0.66) MLYCDKMT2AGAAHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3475085-B1 MULTILAYER FILMS AND PACKAGES FORMED FROM SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2023-07-05 EP disclosed
CN-109195795-B Multilayer film and package formed therefrom 陶氏环球技术有限责任公司 2022-02-18 CN disclosed
EP-3237521-B1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-27 EP disclosed
EP-3237521-B1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-27 EP disclosed
US-10316168-B2 Polyethylene compositions with improved optical properties DOW GLOBAL TECHNOLOGIES LLC (US) 2019-06-11 US disclosed
US-10316168-B2 Polyethylene compositions with improved optical properties DOW GLOBAL TECHNOLOGIES LLC (US) 2019-06-11 US disclosed
EP-3475085-A1 MULTILAYER FILMS AND PACKAGES FORMED FROM SAME Dow Global Technologies LLC (US) 2019-05-01 EP disclosed
US-20190118516-A1 MULTILAYER FILMS AND PACKAGES FORMED FROM SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-25 US disclosed
US-20190118516-A1 MULTILAYER FILMS AND PACKAGES FORMED FROM SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-25 US disclosed
US-20180022894-A1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES DOW GLOBAL TECHNOLOGIES LLC (US) 2018-01-25 US disclosed
US-20180022894-A1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES DOW GLOBAL TECHNOLOGIES LLC (US) 2018-01-25 US disclosed
US-20180022894-A1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES DOW GLOBAL TECHNOLOGIES LLC (US) 2018-01-25 US disclosed
EP-3260295-A1 MULTILAYER FILMS AND PACKAGES FORMED FROM SAME Dow Global Technologies LLC (US) 2017-12-27 EP disclosed
EP-3237521-A1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES Dow Global Technologies LLC (US) 2017-11-01 EP disclosed
WO-2016105610-A1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES DOW GLOBAL TECHNOLOGIES LLC (US) 2016-06-30 WO disclosed
WO-2016105610-A1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES DOW GLOBAL TECHNOLOGIES LLC (US) 2016-06-30 WO disclosed
EP-3037466-A1 Polyethylene compositions with improved optical properties Dow Global Technologies LLC (US) 2016-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180022894-A1 POLYETHYLENE COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES PARG, PARN, FHIT MLYCD 4456/4885KMT2A 1051/4885GAA 2714/4885
US-10316168-B2 Polyethylene compositions with improved optical properties PARG, PARN, FHIT MLYCD 4456/4885KMT2A 1051/4885GAA 2714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.