Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.54 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30921498 | 0.80 | QDPR (0.58) | QDPRTGFBR1ACVR1 | |
| SCHEMBL17664585 | 0.80 | QDPR (0.58) | QDPRTGFBR1ACVR1 | |
| SCHEMBL15490489 | 0.79 | QDPR (0.57) | QDPRTGFBR1ACVR1 | |
| SCHEMBL21037746 | 0.79 | CHRNB2 (0.60) | QDPR | |
| SCHEMBL14923997 | 0.78 | QDPR (0.64) | QDPR | |
| SCHEMBL14925547 | 0.78 | SOS1 (0.38) | — | |
| SCHEMBL7369176 | 0.73 | QDPR (0.72) | QDPRTGFBR1ACVR1 | |
| SCHEMBL24322073 | 0.73 | QDPR (0.50) | QDPRTGFBR1ACVR1 | |
| SCHEMBL1392800 | 0.73 | QDPR (0.50) | QDPR | |
| SCHEMBL30588938 | 0.73 | QDPR (0.50) | QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160096834-A1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2016-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096834-A1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | BTK, SYK, LYN | QDPR 2012/4885TGFBR1 3784/4885ACVR1 4850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.