Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 6/20 | 0.39 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820351 | 0.79 | ALDH1A1 (0.49) | MEN1KMT2AMAPTALOX15ALDH1A1 | |
| SCHEMBL3902134 | 0.79 | HPGD (0.47) | MEN1KMT2AMAPTCYP3A4HPGD | |
| SCHEMBL11722438 | 0.78 | IDO1 (0.56) | MEN1KMT2AMAPTCYP3A4HPGD | |
| SCHEMBL965997 | 0.78 | PYCR1 (0.46) | MEN1KMT2AMAPTPYCR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL31033443 | 0.77 | PYCR1 (0.45) | MEN1KMT2AMAPTPYCR1CYP3A4 | |
| SCHEMBL11255191 | 0.76 | MEN1 (0.57) | MEN1KMT2AMAPTCYP3A4HPGD | |
| SCHEMBL29485890 | 0.76 | PYCR1 (0.47) | MEN1KMT2AMAPTPYCR1CYP3A4 | |
| SCHEMBL979069 | 0.76 | PYCR1 (0.47) | MEN1KMT2AMAPTPYCR1CYP3A4 | |
| SCHEMBL26078400 | 0.76 | PYCR1 (0.47) | MEN1KMT2AMAPTPYCR1CYP3A4 | |
| SCHEMBL980222 | 0.75 | TAAR1 (0.52) | PYCR1CYP3A4TAAR1IDO1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |
| WO-2021003295-A1 | MODULATORS OF HSD17B13 AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |
| WO-2016053855-A1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-04-07 | — | — | WO | disclosed |