Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19136033 | 0.84 | MAPT (0.37) | KAT2BESR1ESR2MAPT | |
| SCHEMBL19524895 | 0.81 | KAT2B (0.33) | KAT2BESR1ESR2 | |
| SCHEMBL4847756 | 0.68 | ESR1 (0.35) | ESR1ESR2 | |
| SCHEMBL3270660 | 0.68 | ESR1 (0.35) | ESR1ESR2 | |
| SCHEMBL18307095 | 0.68 | NR1H2 (0.31) | — | |
| SCHEMBL1270651 | 0.68 | ESR1 (0.42) | ESR1ESR2MAPT | |
| SCHEMBL9225762 | 0.68 | ESR1 (0.42) | ESR1ESR2MAPT | |
| SCHEMBL12191013 | 0.66 | ESR1 (0.41) | ESR1ESR2MAPT | |
| SCHEMBL15391517 | 0.65 | — | — | |
| SCHEMBL21682976 | 0.65 | ABCG2 (0.32) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170210765-A1 | PROCESS FOR PREPARING ALPHA-SILYLAMINE COMPOUNDS FROM ALPHA-SILYLMETHYL AZIDE COMPOUNDS | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2017-07-27 | — | — | US | disclosed |
| WO-2016053017-A1 | PROCESS FOR PREPARING ALPHA-SILYLAMINE COMPOUNDS FROM ALPHA-SILYLMETHYL AZIDE COMPOUNDS | 포항공과대학교 산학협력단 | 2016-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210765-A1 | PROCESS FOR PREPARING ALPHA-SILYLAMINE COMPOUNDS FROM ALPHA-SILYLMETHYL AZIDE COMPOUNDS | ITGAL, MANBA, ITGA1 | KAT2B 1637/4885ESR1 2629/4885ESR2 3546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.