Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13089067 | 0.87 | ESR1 (0.38) | ESR1ESR2MAPTTP53NR1H2 | |
| SCHEMBL14600120 | 0.86 | ESR1 (0.34) | ESR1ESR2MAPTNR1H2NR1H3 | |
| SCHEMBL3454933 | 0.85 | MAPT (0.37) | ESR1ESR2MAPTNR1H2NR1H3 | |
| SCHEMBL4340363 | 0.85 | ESR1 (0.41) | ESR1ESR2MAPTNR1H2NR1H3 | |
| SCHEMBL14600100 | 0.84 | ESR1 (0.33) | ESR1ESR2MAPT | |
| SCHEMBL1270651 | 0.82 | ESR1 (0.42) | ESR1ESR2MAPTTP53NR1H2 | |
| SCHEMBL10611414 | 0.81 | MAOA (0.40) | ESR1ESR2SMN1; SMN2 | |
| SCHEMBL11515549 | 0.81 | MAPT (0.35) | ESR1ESR2MAPTTSHRALDH1A1 | |
| SCHEMBL4660213 | 0.81 | NR1H2 (0.40) | ESR1ESR2MAPTNR1H2NR1H3 | |
| SCHEMBL3238058 | 0.81 | ESR1 (0.34) | ESR1ESR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378430-B1 | Novel organosilicon compound and process for producing organosilicon compound | AGENCY IND SCIENCE TECHN (JP) | 1995-02-01 | — | — | EP | disclosed |
| US-5151538-A | ORGANOSILICON COMPOUND AND PROCESS FOR PRODUCING ORGANOSILICON COMPOUND | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0378430-A1 | Novel organosilicon compound and process for producing organosilicon compound | DIRECTOR-GENERAL OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1990-07-18 | — | — | EP | disclosed |